Evidence map›Paper›PMID 40429981›Full record

ArticleInternational journal of molecular sciences2025

Preliminary Evaluation of Plasma circ_0009910, circ_0027478, and miR-1236-3p as Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma.

Mona Samy Awed, Abeer Ibrahim, Omnia Ezzat, Amal Fawzy, Deema Kamal Sabir, Abdullah F Radwan

Abstract readEvaluation Study
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mona Samy AwedDepartment of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Abeer IbrahimDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11651, Egypt.
Omnia EzzatDepartment of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Amal FawzyDepartment of Clinical Pathology, National Cancer Institute, Cairo University, Cairo 11796, Egypt.
Deema Kamal SabirDepartment of medical surgical Nursing, College of Nursing, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0009-0009-8840-8791
Abdullah F RadwanDepartment of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.ORCID 0000-0002-3731-1561

Funding

Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia PNURSP2024R446
6 · The paper itself

Abstract

Circular RNAs (circRNAs) are increasingly recognized as significant regulators in multiple cancers, such as hepatocellular carcinoma (HCC), frequently affecting microRNA (miRNA) expression. The diagnostic and prognostic roles of circRNAs, specifically

Indexed as

Biomarkers, TumorCarcinoma, HepatocellularLiver NeoplasmsMicroRNAsRNA, CircularAdultAgedAged, 80 and overFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedPrognosisBiomarkers, TumorMicroRNAsMIRN1236 microRNA, humanRNA, Circularcirc_0009910circ_0027478circRNAshepatocellular carcinoma (HCC)miR-1236-3plasma biomarkers

Identifiers

PMID40429981
PMCPMC12111893

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.