Evidence map›Paper›PMID 40429952›Full record

ArticleInternational journal of molecular sciences2025

Bisphenol A in the Urine: Association with Urinary Creatinine, Impaired Kidney Function, Use of Plastic Food and Beverage Storage Products but Not with Serum Anti-Müllerian Hormone in Ovarian Malignancies.

Mateja Sladič, Špela Smrkolj, Gorazd Kavšek, Senka Imamovic-Kumalic, Ivan Verdenik, Irma Virant-Klun

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mateja SladičDivision of Gynaecology and Obstetrics, University Medical Centre, 1000 Ljubljana, Slovenia.
Špela SmrkoljDivision of Gynaecology and Obstetrics, University Medical Centre, 1000 Ljubljana, Slovenia.ORCID 0000-0001-9698-2130
Gorazd KavšekDivision of Gynaecology and Obstetrics, University Medical Centre, 1000 Ljubljana, Slovenia.
Senka Imamovic-KumalicDivision of Gynaecology and Obstetrics, University Medical Centre, 1000 Ljubljana, Slovenia.
Ivan VerdenikDivision of Gynaecology and Obstetrics, University Medical Centre, 1000 Ljubljana, Slovenia.ORCID 0000-0001-6249-5799
Irma Virant-KlunClinical Research Centre, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.

Funding

The Slovenian Research and Innovation Agency J3-2530
6 · The paper itself

Abstract

Bisphenol A (BPA) is a high-production-volume industrial chemical and component of commonly used plastic products. However, it is also an endocrine-disrupting chemical that can negatively affect human health. It is not yet known whether it is associated with the development of epithelial ovarian cancer (EOC), a severe and highly fatal human disease. Therefore, the purpose of this study was to determine the concentrations of BPA in the urine of women with EOC or epithelial borderline ovarian tumors (EBOTs) using gas chromatography tandem mass spectrometry (GC-MS/MS) and find their possible associations with kidney function at the molecular level, urine and blood biochemical parameters related to metabolism, anti-Müllerian hormone (AMH) (a marker of ovarian reserve/fertility), and lifestyle habits determined via a questionnaire in comparison to healthy controls. The results suggest that the unadjusted or urine-specific-gravity-adjusted BPA levels were significantly increased in women with EOC/EBOT. The unadjusted BPA was significantly positively associated with urinary creatinine (

Indexed as

Anti-Mullerian HormoneBenzhydryl CompoundsCarcinoma, Ovarian EpithelialCreatinineOvarian NeoplasmsPhenolsAdultBeveragesBisphenol A CompoundsFemaleGas Chromatography-Mass SpectrometryHumansMiddle AgedPlasticsAnti-Mullerian HormoneBenzhydryl Compoundsbisphenol ABisphenol A CompoundsCreatininePhenolsPlasticsanti-Müllerian hormonebisphenol Aborderline ovarian tumorfemale exposurekidney functionlifestyle habitsovarian cancerthrombocytesurine

Identifiers

PMID40429952
PMCPMC12112075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.