Evidence map›Paper›PMID 40429933›Full record

ArticleInternational journal of molecular sciences2025

Skin Fibroblasts from Individuals Self-Diagnosed as Electrosensitive Reveal Two Distinct Subsets with Delayed Nucleoshuttling of the ATM Protein in Common.

Laurène Sonzogni, Joëlle Al-Choboq, Patrick Combemale, Amélie Massardier-Pilonchéry, Audrey Bouchet, Philippe May, Jean-François Doré, Jean-Claude Debouzy, Michel Bourguignon, Yves Le Dréan and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laurène SonzogniUnité Mixte de Recherche (UMR)1296 «Radiation: Defense, Health, Environment», Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Léon-Bérard, 69008 Lyon, France.
Joëlle Al-ChoboqUnité Mixte de Recherche (UMR)1296 «Radiation: Defense, Health, Environment», Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Léon-Bérard, 69008 Lyon, France.ORCID 0000-0001-6772-6947
Patrick CombemaleUnité Mixte de Recherche (UMR)1296 «Radiation: Defense, Health, Environment», Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Léon-Bérard, 69008 Lyon, France.
Amélie Massardier-PilonchéryUniversity Claude-Bernard Lyon 1, University Gustave-Eiffel, Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement (UMRESTTE), UMR_T9405, 690008 Lyon, France.
Audrey BouchetUnité Mixte de Recherche (UMR)1296 «Radiation: Defense, Health, Environment», Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Léon-Bérard, 69008 Lyon, France.ORCID 0000-0001-7228-8830
Philippe MayInstitut de Recherche Biomédicale des Armées, 1 Place du Générale Valérie André, BP 40073, 91223 Brétigny-sur-Orge, France.
Jean-François DoréUnité Mixte de Recherche (UMR)1296 «Radiation: Defense, Health, Environment», Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Léon-Bérard, 69008 Lyon, France.
Jean-Claude DebouzyInstitut de Recherche Biomédicale des Armées, 1 Place du Générale Valérie André, BP 40073, 91223 Brétigny-sur-Orge, France.
Michel BourguignonUnité Mixte de Recherche (UMR)1296 «Radiation: Defense, Health, Environment», Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Léon-Bérard, 69008 Lyon, France.ORCID 0000-0002-4575-5840
Yves Le DréanInserm, Ecole des Hautes Etudes en Santé Publique (EHSEP), Institut de Recherche en Santé, Environnement et Travail (IRSET), University of Rennes, UMR_S 1085, 35000 Rennes, France.
Nicolas ForayUnité Mixte de Recherche (UMR)1296 «Radiation: Defense, Health, Environment», Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Léon-Bérard, 69008 Lyon, France.ORCID 0000-0002-1282-1303

Funding

ANSES DEMETER studyCommissariat à l'Investissement INDIRA
6 · The paper itself

Abstract

Electromagnetic hyper-sensitivity (EHS) and its causal link with radio-frequencies raise a major question of public health. In the frame of the clinical study DEMETER, 26 adult volunteers self-diagnosed as EHS-positive agreed to reply to a self-assessment questionnaire and to provide a skin biopsy sampling to establish a primary fibroblast cell line. The questionnaire and the biological data revealed, independently, 2 subsets of donors associated each with a low background, highly responsive (LBHR) and a high background, lowly responsive (HBLR) phenotype. A couple of subsets based on questionnaire data and based on the yield of spontaneous DNA double-strand breaks were found to be composed of the same donors at 64% identity. After exposure to X-rays, and application of anti-

Indexed as

FibroblastsSkinAtaxia Telangiectasia Mutated ProteinsBiomarkersCells, CulturedElectromagnetic FieldsGenetic LociHistonesHumansHydrogen PeroxideMRE11 Homologue ProteinSurveys and QuestionnairesAtaxia Telangiectasia Mutated ProteinsATM protein, humanBiomarkersH2AX protein, humanHistonesHydrogen PeroxideMRE11 Homologue ProteinMRE11 protein, humanATMDNA double-strand breaksDSB repairEHSelectrosensitivityEMFimmunofluorescenceoxidative stressradiosensitivityself-assessment questionnaire

Identifiers

PMID40429933
PMCPMC12112057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.