Evidence map›Paper›PMID 40429922›Full record

ReviewInternational journal of molecular sciences2025

Advances in Genome Editing Through Haploid Induction Systems.

Huajin Sheng, Peng Gao, Changye Yang, Teagen D Quilichini, Leon V Kochian, Raju Datla, Daoquan Xiang

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Genome Editing by Grafting.International journal of molecular sciences · 2025
    Review
  6. Haploid Production inBiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huajin ShengDepartment of Biology, College of Arts and Science, University of Saskatchewan, Saskatoon, SK S7N 5E2, Canada.
Peng GaoAgriculture and Agri-Food Canada, Saskatoon Research and Development Centre, 107 Science Place, Saskatoon, SK S7N 0X2, Canada.ORCID 0000-0002-6586-4307
Changye YangAquatic and Crop Resource Development, National Research Council Canada, Saskatoon, SK S7N 0W9, Canada.
Teagen D QuilichiniDepartment of Biology, College of Arts and Science, University of Saskatchewan, Saskatoon, SK S7N 5E2, Canada.ORCID 0000-0003-3311-3776
Leon V KochianDepartment of Plant Sciences, University of Saskatchewan, Saskatoon, SK S7N 5A8, Canada.ORCID 0000-0003-3416-089X
Raju DatlaGlobal Institute for Food Security, University of Saskatchewan, Saskatoon, SK S7N 4J8, Canada.ORCID 0000-0003-0790-5569
Daoquan XiangAquatic and Crop Resource Development, National Research Council Canada, Saskatoon, SK S7N 0W9, Canada.ORCID 0000-0001-7144-1274

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Groundbreaking advances in gene editing technologies are transforming modern plant breeding by enabling precise genetic modifications that dramatically accelerate crop improvement. Haploid and diploid induction systems have emerged as particularly powerful tools in this landscape, offering both efficient gene editing capabilities and rapid production of homozygous lines while seamlessly integrating with the advanced genome-editing platforms such as CRISPR-Cas systems. This review synthesizes the current state of knowledge regarding the mechanisms, applications, and recent progress in haploid and diploid induction systems for gene editing. We examine their transformative potential for enhancing genetic gains and compressing breeding timelines, with significant implications for global food security. Additionally, we provide a critical analysis of emerging challenges of genome editing in crops and outline promising future directions for research and development.

Indexed as

Crops, AgriculturalGene EditingGenome, PlantHaploidyCRISPR-Cas SystemsDiploidyPlant BreedingPlants, Genetically Modifieddouble haploidgene editinghaploid inductionmaternal haploid inducerpaternal haploid inducer

Identifiers

PMID40429922
PMCPMC12112045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.