Evidence map›Paper›PMID 40429842›Full record

ReviewInternational journal of molecular sciences2025

P-Glycoprotein as a Therapeutic Target in Hematological Malignancies: A Challenge to Overcome.

Pablo Álvarez-Carrasco, Fernanda Morales-Villamil, Carmen Maldonado-Bernal

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pablo Álvarez-CarrascoLaboratorio de Investigación en Inmunología y Proteómica, Hospital Infantil de México Federico Gómez, Mexico City 06720, Mexico.
Fernanda Morales-VillamilLaboratorio de Investigación en Inmunología y Proteómica, Hospital Infantil de México Federico Gómez, Mexico City 06720, Mexico.
Carmen Maldonado-BernalLaboratorio de Investigación en Inmunología y Proteómica, Hospital Infantil de México Federico Gómez, Mexico City 06720, Mexico.ORCID 0000-0003-0663-2888

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

P-glycoprotein (P-gp), a transmembrane efflux pump encoded by the

Indexed as

Antineoplastic AgentsATP Binding Cassette Transporter, Subfamily B, Member 1Hematologic NeoplasmsAnimalsATP Binding Cassette Transporter, Subfamily BDrug Delivery SystemsDrug Resistance, MultipleDrug Resistance, NeoplasmHumansMolecular Targeted TherapySignal TransductionAntineoplastic AgentsATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1hematological malignanciesmultidrug resistanceP-glycoproteintherapeutic target

Identifiers

PMID40429842
PMCPMC12112708

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.