ReviewInternational journal of molecular sciences2025
Pharmacological Effects and Immune Mechanisms of Oriental Medicines in Restoring Male Infertility.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- A mechanistic study on the repair of cadmium-induced male infertility using Yishen Tongluo formula based on network toxicology and experimental validation.Frontiers in endocrinology · 2026Article
- Immunological mechanisms and precision stratification in male infertility: from testicular immune privilege and danger signal amplification to seminal immune biomarkers and mechanism-tailored intervention.Frontiers in immunology · 2026Review
- Nor1 and Mitophagy: An Insight into Sertoli Cell Function Regulating Spermatogenesis Using a Transgenic Rat Model.International journal of molecular sciences · 2025Article
- Wuzi-Yanzong-Wan inhibits testicular mitochondrial apoptosis in rats by downregulating TAp73-Mediated P38 MAPK-ADAM17 pathway.Frontiers in pharmacology · 2025Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Male infertility can be the result of many factors, including pathologies in the motility and formation of sperm and obstructions in the genitourinary system. Oriental medicine, using multiple components to address various targets and enhance therapeutic effectiveness, has been used to treat male infertility for thousands of years. Given the complex pathological mechanisms of aspermatogenesis, this multi-target approach in oriental medicine is believed to positively impact the prevention of male infertility. Efforts have been made to evaluate the pharmacological properties of many herbs. However, the testicular immune responses and mechanisms of these oriental medicines remain unclear from a modern scientific perspective. Some studies reviewed here have reported on the recovery of spermatogenesis in infertility, the available research that evaluates the efficacy of oriental medicines in the treatment of aspermatogenesis and briefly summarizes the available rodent and human data on facilitating immunological differences in male infertility. These findings augment the current understanding of the immune mechanisms of oriental medicine as a treatment solution for male infertility.
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