Evidence map›Paper›PMID 40429769›Full record

ArticleInternational journal of molecular sciences2025

Apoptosis and G2/M Phase Cell Cycle Arrest Induced by Alkaloid Erythraline Isolated from

Cleine Aglacy Nunes Miranda, Amaxsell Thiago Barros de Souza, Ana Katarina Menezes da Cruz Soares, Emanuelly Bernardes-Oliveira, Hugo Alexandre Oliveira Rocha, Euzébio Guimarães Barbosa, Thais Guaratini, Norma Lucena-Silva, Ricardo Ney Cobucci, Raquel Brandt Giordani and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cleine Aglacy Nunes MirandaPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Rio Grande do Norte, Natal 52171-900, RN, Brazil.
Amaxsell Thiago Barros de SouzaPostgraduate Program in Sciences Applied to Women's Health, Federal University of Rio Grande do Norte, Natal 59012-310, RN, Brazil.ORCID 0000-0002-7085-8788
Ana Katarina Menezes da Cruz SoaresDepartment of Biochemistry, Federal University of Rio Grande do Norte, Natal 59064-741, RN, Brazil.
Emanuelly Bernardes-OliveiraPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Rio Grande do Norte, Natal 52171-900, RN, Brazil.
Hugo Alexandre Oliveira RochaDepartment of Biochemistry, Federal University of Rio Grande do Norte, Natal 59064-741, RN, Brazil.ORCID 0000-0003-2252-1221
Euzébio Guimarães BarbosaDepartment of Pharmacy, Federal University of Rio Grande do Norte, Natal 59012-570, RN, Brazil.ORCID 0000-0002-7685-9618
Thais GuaratiniLychnoflora Research and Development in Natural Products LTDA, Ribeirão Preto 14040-900, SP, Brazil.ORCID 0000-0002-7028-6871
Norma Lucena-SilvaDepartment of Immunology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Recife 50670-465, PE, Brazil.ORCID 0000-0002-6140-1794
Ricardo Ney CobucciPostgraduate Program in Sciences Applied to Women's Health, Federal University of Rio Grande do Norte, Natal 59012-310, RN, Brazil.ORCID 0000-0002-0184-2061
Raquel Brandt GiordaniDepartment of Pharmacy, Federal University of Rio Grande do Norte, Natal 59012-570, RN, Brazil.
Janaina Cristiana de Oliveira CrispimPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Rio Grande do Norte, Natal 52171-900, RN, Brazil.ORCID 0000-0002-1344-0078

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) 001
6 · The paper itself

Abstract

Cervical cancer remains a significant global health concern, causing more than 300,000 deaths annually.

Indexed as

AlkaloidsAntineoplastic Agents, PhytogenicApoptosisErythrinaG2 Phase Cell Cycle CheckpointsM Phase Cell Cycle CheckpointsUterine Cervical NeoplasmsCell Line, TumorCell ProliferationFemaleHumansMolecular Docking SimulationPlant ExtractsAlkaloidsAntineoplastic Agents, PhytogenicPlant Extractsapoptosiscell cycle arrestcervical cancererythralineSiHa cells

Identifiers

PMID40429769
PMCPMC12111132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.