Evidence map›Paper›PMID 40429649›Full record

ArticleInternational journal of molecular sciences2025

Nitazoxanide Analogs: Synthesis, In Vitro Giardicidal Activity, and Effects on

Laura Morales-Luna, Beatriz Hernández-Ochoa, Abigail González-Valdez, Montserrat Vázquez-Bautista, Roberto Arreguin-Espinosa, Verónica Pérez de la Cruz, Sergio Enríquez-Flores, Ignacio De la Mora De la Mora, Elizabeth Hernández-Urzúa, Rosa Angélica Castillo-Rodríguez and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Advances in pharmacological and pharmaceutical sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Laura Morales-LunaLaboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City 04530, Mexico.ORCID 0000-0002-7194-4522
Beatriz Hernández-OchoaLaboratorio de Inmunoquímica, Hospital Infantil de México Federico Gómez, Secretaría de Salud, Mexico City 06720, Mexico.
Abigail González-ValdezDepartamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Montserrat Vázquez-BautistaLaboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City 04530, Mexico.ORCID 0009-0002-4651-7892
Roberto Arreguin-EspinosaDepartamento de Química de Biomacromoléculas, Instituto de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-4611-4770
Verónica Pérez de la CruzNeurobiochemistry and Behavior Laboratory, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", Mexico City 14269, Mexico.ORCID 0000-0002-1451-8754
Sergio Enríquez-FloresLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City 04530, Mexico.ORCID 0000-0003-2058-5707
Ignacio De la Mora De la MoraLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City 04530, Mexico.ORCID 0000-0002-5654-8089
Elizabeth Hernández-UrzúaLaboratorio de Toxicología Genética, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City 04530, Mexico.
Rosa Angélica Castillo-RodríguezCentro de Investigación en Ciencia Aplicada y Tecnología Avanzada (CICATA) Unidad Morelos, Instituto Politécnico Nacional, Boulevard de la Tecnología, 1036 Z-1, P 2/2, Atlacholoaya 62790, Mexico.ORCID 0000-0003-4117-6689
Noemí Cárdenas-RodríguezLaboratorio de Neurociencias, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City 04530, Mexico.ORCID 0000-0002-6580-3440
Víctor Martínez-RosasDepartamento de Ingeniería Química y Bioquímica, Instituto Tecnológico de Milpa Alta, Tecnológico Nacional de México, Milpa Alta, Mexico City 12300, Mexico.ORCID 0000-0001-6137-6499
Gabriel Navarrete-VázquezFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Chamilpa, Cuernavaca 62209, Mexico.ORCID 0000-0001-5344-4762
Saúl Gómez-ManzoLaboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, Mexico City 04530, Mexico.ORCID 0000-0003-2095-9182

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías (CONAHCYT) Ciencia de Frontera 2023 CF-2023-I-811E022 Program, National Institute of Pediatrics, Mexico City, Mexico (Recursos Fiscales para la Investigación) INP 021/2022Fondos Federales HIM/2019/036 SSA. 1595
6 · The paper itself

Abstract

Giardiasis is a common intestinal infection caused by

Indexed as

Antiprotozoal AgentsGiardia lambliaThiazolesDrug ResistanceGene Expression RegulationGiardiasisNitro CompoundsProtozoan ProteinsTrophozoitesAntiprotozoal AgentsnitazoxanideNitro CompoundsProtozoan ProteinsThiazolesantigiardial activitygene expressionGiardia lamblianitrothiazole

Identifiers

PMID40429649
PMCPMC12111156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.