Evidence map›Paper›PMID 40429588›Full record

ReviewJournal of clinical medicine2025

Limus Devices for the Treatment of SFA: Latest Outcomes and Future Perspectives.

Genti Xhepa, Agostino Inzerillo, Ilinca Constantinescu, Pierre Faerber, Adrien Gleyzolle, Pierpaolo Biondetti, Filippo Del Grande, Edon Xhepa, Simone Mortellaro, Gianpaolo Carrafiello and 2 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Genti XhepaIstituto di Imaging della Svizzera Italiana (IIMSI), Ente Ospedaliero Cantonale (EOC), 6900 Lugano, Switzerland.ORCID 0000-0002-4291-7875
Agostino InzerilloAOUP Paolo Giaccone, Biomedicine, Neuroscience and Advanced Diagnostic Department (BiND), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-3132-2921
Ilinca ConstantinescuInterventional Radiology Unit, University Hospital of Geneva (HUG), 1205 Geneva, Switzerland.
Pierre FaerberInterventional Radiology Unit, University Hospital of Geneva (HUG), 1205 Geneva, Switzerland.ORCID 0009-0001-0564-1654
Adrien GleyzolleInterventional Radiology Unit, University Hospital of Geneva (HUG), 1205 Geneva, Switzerland.ORCID 0009-0008-4524-4857
Pierpaolo BiondettiDepartment of Radiology, Foundation IRCCS Ca' Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-2737-2053
Filippo Del GrandeIstituto di Imaging della Svizzera Italiana (IIMSI), Ente Ospedaliero Cantonale (EOC), 6900 Lugano, Switzerland.ORCID 0000-0003-1106-5830
Edon XhepaPostgraduate School in Radiodiagnostics, University of Milan, 20122 Milan, Italy.
Simone MortellaroPostgraduate School in Radiodiagnostics, University of Milan, 20122 Milan, Italy.
Gianpaolo CarrafielloDepartment of Radiology, Foundation IRCCS Ca' Granda-Ospedale Maggiore Policlinico, University of Milan, 20122 Milan, Italy.
Giuseppe PellegrinoPostgraduate School in Radiodiagnostics, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-0992-0028
Alexis RicoeurInterventional Radiology Unit, University Hospital of Geneva (HUG), 1205 Geneva, Switzerland.ORCID 0000-0001-5443-8428

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, cardiovascular disease is a leading cause of disability and early death, affecting 422.7 million people and causing 17.9 million deaths (31% of global deaths) in 2015. Peripheral arterial disease, previously overlooked compared to coronary artery disease, is now recognised as a major contributor to cardiovascular morbidity and mortality, with distinct characteristics. After noninvasive methods, the femoropopliteal segment is frequently treated with revascularisation, which is recommended for claudication and chronic limb-threatening ischemia (CLTI). Challenges such as mechanical stresses, chronic occlusions, extensive plaque, and calcification affect procedural success and vessel patency. Innovations were needed to address these issues, and vascular drug delivery devices have become integral to endovascular treatment. We review the current literature concerning a diverse range of these devices in clinical use and their role in managing symptomatic patients.

Indexed as

bioresorbable scaffoldsdrug-eluting balloondrug-eluting stentendovascular treatmentpaclitaxelpopliteal arterysirolimussuperficial femoral artery

Identifiers

PMID40429588
PMCPMC12112002

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.