Evidence map›Paper›PMID 40429526›Full record

ReviewJournal of clinical medicine2025

Endoscopic Management of Ampullary Adenomas: A Comprehensive Review.

Minh Thu T Nguyen, Ruchir Paladiya, Dushyant Singh Dahiya, Murali Dharan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minh Thu T NguyenDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.ORCID 0000-0002-4367-1248
Ruchir PaladiyaDepartment of Internal Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.
Dushyant Singh DahiyaDivision of Gastroenterology, Hepatology and Motility, The University of Kansas School of Medicine, Kansas City, KS 66160, USA.ORCID 0000-0002-8544-9039
Murali DharanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.ORCID 0000-0002-9764-0068

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ampullary adenomas are rare outgrowths at the ampulla of Vater that may progress into cancer via the adenoma-to-carcinoma sequence, particularly in individuals with hereditary polyposis syndrome. Many are diagnosed incidentally or once the lesion becomes large enough to cause obstruction. Traditionally managed surgically with high morbidity and mortality, advances in imaging and therapy have made endoscopic ampullectomy the first-line treatment for noninvasive lesions. Despite its high success rate and favorable safety profile, complications such as pancreatitis, ductal stenosis, bleeding, recurrence, and perforation can occur. Recommendations for optimal endoscopic techniques and surveillance intervals are largely based on expert opinion in interventional endoscopy and findings from small-scale studies. This review provides an updated framework for the diagnosis and management of ampullary adenomas.

Indexed as

ampullary adenocarcinomaampullary adenomaendoscopic ampullectomyendoscopic retrograde cholangiopancreatographyendoscopic ultrasound

Identifiers

PMID40429526
PMCPMC12112356

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.