Evidence map›Paper›PMID 40429465›Full record

ArticleJournal of clinical medicine2025

When Real-World Outcomes Do Not Meet the Results of Clinical Trials: Transfemoral Transcatheter vs. Surgical Aortic Valve Replacement in an Intermediate-Age Population (The Outstanding Italy Study).

Marco Ranucci, Lidia Staszewsky, Massimo Cartabia, Mauro Tettamanti, Vito Lepore, Fabio Robusto, Antonio Clavenna, Antonio D'Ettorre, Eloisa Arbustini, Damiano Baldassarre and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Marco RanucciDepartment of Cardiovascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, 20097 Milan, Italy.ORCID 0000-0002-4915-3572
Lidia StaszewskyLaboratory Clinical Research in Brain and Cardiovascular Injury, Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Massimo CartabiaLaboratory of Geriatric Neuropsychiatry, Department of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.ORCID 0000-0002-3794-4772
Mauro TettamantiLaboratory of Geriatric Neuropsychiatry, Department of Health Policy, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.ORCID 0000-0001-7345-0887
Vito LeporeLaboratory of Medical Research and Consumer Involvement, Department of Public Health, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Fabio RobustoPuglia Health System, Medonline-Statte, ASL-TA, 74010 Taranto, Italy.
Antonio ClavennaScientific Department, Centre for Inherited Cardiovascular Diseases, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0001-5536-4192
Antonio D'EttorrePuglia Health System, Medonline-Statte, ASL-TA, 74010 Taranto, Italy.ORCID 0000-0002-5880-4234
Eloisa ArbustiniScientific Department, Centre for Inherited Cardiovascular Diseases, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Damiano BaldassarreCentro Cardiologico Monzino, IRCCS, 20138 Milan, Italy.
Maria Teresa La RovereDepartment of Cardiology, Istituti Clinici Scientifici Maugeri, Montescano Institute-IRCCS, 27040 Montescano, Italy.ORCID 0000-0002-1884-5058
Matteo MontorfanoSchool of Medicine, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Gianfranco ParatiIstituto Auxologico Italiano, S. Luca Hospital, University of Milan-Bicocca, 20126 Milan, Italy.ORCID 0000-0001-9402-7439
Roberto F E PedrettiSchool of Medicine and Surgery, University of Milano Bicocca, 20126 Milano, Italy.ORCID 0000-0003-1789-8657
Giuseppe Maria RaffaDepartment for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT, 90127 Palermo, Italy.ORCID 0000-0001-7141-2561
Francesco SantiniCardiac Surgery, Ospedale Policlinico San Martino, University of Genoa, 16126 Genoa, Italy.
Giulio StefaniniIRCCS Istituto Clinico Humanitas, 20089 Rozzano, Italy.ORCID 0000-0002-3558-6967
Maurizio VolterraniCardiopulmonary Department, IRCCS San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0002-2624-9213
Ida FortinoPuglia Health System, Agenzia Regionale Strategica per la Salute ed il Sociale, AReSS Puglia, Area Epidemiologia e Care Intelligence, 70121 Bari, Italy.
Lucia BiscegliaLaboratory for Pharmacoepidemiology, Department of Public Health, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
Lorenzo MenicantiDepartment of Cardiac Surgery, IRCCS Policlinico San Donato, 20097 Milan, Italy.
Roberto LatiniLaboratory Clinical Research in Brain and Cardiovascular Injury, Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.

Funding

Italian Ministry of Health N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aortic valve stenosisoutcomesurgical aortic valve replacementtranscatheter aortic valve implantation

Identifiers

PMID40429465
PMCPMC12539603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.