Evidence map›Paper›PMID 40429384›Full record

ReviewJournal of clinical medicine2025

Treatment of Pancreatic Neuroendocrine Tumors: Beyond Traditional Surgery and Targeted Therapy.

Khyati Bidani, Angela G Marinovic, Vishali Moond, Prateek Harne, Arkady Broder, Nirav Thosani

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07625189 (Prospective Observational Registry of EUS-Guided Ablation), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07625189 recruitingnot on this mapstarted 2026, after this paper: background citation

Prospective Observational Registry of EUS-Guided Ablation (RFA and MWA) for Pancreatic and Other Gastrointestinal Lesions

Typeobservational_patient_registrySponsorWest Virginia UniversityRan2026 to 2028Enrolled50ConditionsRFA, Microwave Ablation, Pancreatic Lesion, Gastrointestinal Lesions
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khyati BidaniDepartment of Internal Medicine, Saint Peter's University Hospital/Rutgers, New Brunswick, NJ 08901, USA.
Angela G MarinovicDepartment of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0009-0003-1988-5435
Vishali MoondDepartment of Gastroenterology & Hepatology, West Virginia University, Morgantown, WV 26506, USA.
Prateek HarneDepartment of Advanced Endoscopy, Allegheny General Hospital, Pittsburgh, PA 15212, USA.ORCID 0000-0002-7904-6890
Arkady BroderDivision of Gastroenterology, Saint Peter's University Hospital/Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
Nirav ThosaniCenter for Interventional Gastroenterology at UTHealth (iGUT), Department of Surgery, Division of Endoluminal Surgery and Interventional Gastroenterology, McGovern Medical School at UTHealth, Houston, TX 77030, USA.ORCID 0000-0002-4607-6241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine tumors (PNETs) are a rare subset of pancreatic neoplasms with diverse biological behavior and clinical presentations. Traditional treatment approaches, such as surgery and targeted therapies, have significantly improved outcomes. However, advancements in molecular biology, immunotherapy, and minimally invasive techniques have ushered in a new era of treatment possibilities. This manuscript explores the emerging modalities in PNET management, emphasizing the need for a multidisciplinary approach tailored to individual patient profiles.

Indexed as

conversion surgeryEUS-guided ablationimmunotherapy advancementsmicrowave ablationminimally invasive techniquesmolecularneoadjuvant and adjuvant therapypancreatic neuroendocrine tumors (PNETs)peptide receptor radionuclide therapy (PRRT)radiofrequency ablationsomatostatin analogstargeted therapy

Identifiers

PMID40429384
PMCPMC12112752

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.