Evidence map›Paper›PMID 40428715›Full record

ArticleMicromachines2025

A Multifunctional Capsule-like Puncture Biopsy Robot for the Gastrointestinal System.

Xinmiao Xu, Jinghan Gao, Dingwen Tong, Yiqun Zhao, Xinjian Fan, Wanning Ge

Abstract read
In one paragraph

Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinmiao XuSchool of Future Science and Engineering, Soochow University, Suzhou 215222, China.
Jinghan GaoSchool of Future Science and Engineering, Soochow University, Suzhou 215222, China.
Dingwen TongSchool of Future Science and Engineering, Soochow University, Suzhou 215222, China.
Yiqun ZhaoSchool of Future Science and Engineering, Soochow University, Suzhou 215222, China.
Xinjian FanSchool of Future Science and Engineering, Soochow University, Suzhou 215222, China.
Wanning GeSchool of Mechanical and Electrical Engineering, Soochow University, Suzhou 215131, China.

Funding

National Key Research and Development Project 2023YFB470530National Natural Science Foundation of China 6192530National Natural Science Foundation of China 62103294National Natural Science Foundation of China 62422313Undergraduate Training Program for Innovation and Entrepreneurship, Soochow University 202410285107Z
6 · The paper itself

Abstract

Gastrointestinal submucosal tumors (SMTs) are difficult to diagnose accurately due to their deep location and the limitations of traditional biopsy tools. To address these issues, we propose a multifunctional capsule-shaped puncture biopsy robot (PBR) with capabilities for tissue sampling, thermal hemostasis, and multi-stage drug delivery. The PBR measures 27 mm in length and 13 mm in diameter, integrating a micro-scale electro-permanent magnetic system with a 60-turn dual-layer coil (wire diameter: 0.6 mm) to drive an 8 mm-depth puncture needle. A graphene-carbon nanotube composite heating film enables rapid and safe temperature elevation, achieving effective hemostasis and triggering sequential drug release using paraffin-based phase-change materials. Heating remains within the clinical safety range. Experiments demonstrated successful tissue penetration, precise magnetic control, and reliable staged pigment release simulating drug delivery. Tests on an ex vivo porcine stomach confirmed adaptability to irregular gastric surfaces. This compact PBR provides an integrated and minimally invasive approach to both the diagnosis and treatment of gastrointestinal lesions.

Indexed as

micro-electromagnetic actuatorpuncture biopsy robotsubmucosal tumorstargeted drug deliverythermal hemostasis

Identifiers

PMID40428715
PMCPMC12113727

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.