Evidence map›Paper›PMID 40428631›Full record

ArticleMicromachines2025

Characterization of the Coating Layers Deposited onto Curved Surfaces Using a Novel Multi-Nozzle Extrusion Printer.

Ramses Seferino Trigo Torres, Lawrence Kulinsky, Arash Kheradvar

Abstract read
In one paragraph

Article in Micromachines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ramses Seferino Trigo TorresDepartment of Biomedical Engineering, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0000-0002-5048-3691
Lawrence KulinskyDepartment of Mechanical and Aerospace Engineering, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0000-0002-1176-3578
Arash KheradvarDepartment of Biomedical Engineering, University of California-Irvine, Irvine, CA 92697, USA.ORCID 0000-0003-3864-1359

Funding

Volumetric Echocardiographic Particle Image Velocimetry for Grading the Severity of Mitral Valve RegurgitationR01HL153724 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Arash Kheradvar · 2022 to 2026
$3.9M
Computational and Experimental Modeling of Subclinical Leaflet Thrombosis in Bioprosthetic Aortic ValvesR01HL157631 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FOGELSON, AARON L, GRIFFITH, BOYCE EUGENE · 2022 to 2025
$2.7M
Reciprocal effects between scaffold geometry and ventricular vortex flow on viability and performance of tissue-engineered mitral valveR01HL162687 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Arash Kheradvar · 2023 to 2026
$2.3M
High-speed 4D echocardiography system with adjustable multi-planar acquisitionR56HL173809 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KHERADVAR, ARASH, YEN, JESSE T-P · 2024 to 2024
$678k
NHLBI NIH HHS R01 HL153724NHLBI NIH HHS R01 HL157631NHLBI NIH HHS R01 HL162687NHLBI NIH HHS R56 HL173809NIH HHS 1R01HL157631-22A1NIH HHS 1R01HL162687-23A3
6 · The paper itself

Abstract

Over the past two decades, additive manufacturing has advanced significantly, enabling rapid fabrication of functional components across various applications. In medical devices, it has been used for prototyping, prosthetics, drug delivery platforms, and more recently, tissue scaffolding. However, current technologies face challenges, particularly in depositing conformal layers over curved surfaces. This study introduces a novel multi-nozzle extrusion printer concept designed to deposit soft gel layers onto curved surfaces. A custom clearance locking mechanism enhances the printer's ability to achieve conformal coatings on both flat and curved substrates. We investigate key deposition parameters, including displacement volume and nozzle configuration, while comparing two deposition sequences: "Press and Express" and "Express and Press". Our results demonstrate that the "Express and Press" technique yields more uniform, merged conformal layers than the "Press and Express" method. This technology holds promise for further refinement and potential applications in tissue engineering.

Indexed as

3D printingbioprintingcoatingextrusionprototypingtissue engineering

Identifiers

PMID40428631
PMCPMC12113764

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.