Evidence map›Paper›PMID 40428559›Full record

ArticleFoods (Basel, Switzerland)2025

Procyanidins and Anthocyanins in Young and Aged Prokupac Wines: Evaluation of Their Reactivity Toward Salivary Proteins.

Katarina Delić, Danijel D Milinčić, Aleksandar V Petrović, Slađana P Stanojević, Anne-Laure Gancel, Michael Jourdes, Mirjana B Pešić, Pierre-Louis Teissedre

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katarina DelićInstitute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11080 Belgrade, Serbia.
Danijel D MilinčićInstitute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11080 Belgrade, Serbia.ORCID 0000-0002-2476-9426
Aleksandar V PetrovićInstitute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11080 Belgrade, Serbia.ORCID 0000-0002-7105-7456
Slađana P StanojevićInstitute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11080 Belgrade, Serbia.ORCID 0000-0001-5740-8267
Anne-Laure GancelBordeaux Sciences Agro, Bordeaux INP, Université de Bordeaux, UMR 1366 OENOLOGIE, ISVV, 33140 Villenave d'Ornon, France.ORCID 0000-0002-3958-2779
Michael JourdesBordeaux Sciences Agro, Bordeaux INP, Université de Bordeaux, UMR 1366 OENOLOGIE, ISVV, 33140 Villenave d'Ornon, France.ORCID 0000-0002-5436-5238
Mirjana B PešićInstitute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11080 Belgrade, Serbia.ORCID 0000-0001-9779-1686
Pierre-Louis TeissedreBordeaux Sciences Agro, Bordeaux INP, Université de Bordeaux, UMR 1366 OENOLOGIE, ISVV, 33140 Villenave d'Ornon, France.ORCID 0000-0002-0115-5456

Funding

French Embassy in Serbia/French Institute (French Ministry of Foreign Affairs) scholarship 2021-2024Ministry of Science, Technological Development, and Innovation of the Republic of Serbia 451-03-65/2024-03/200116Ministry of Science, Technological Development, and Innovation of the Republic of Serbia 451-03- 66/2024-03/200026the Science Fund of Republic of Serbia 7744714, FUNPRO
6 · The paper itself

Abstract

In this study, the reactivity of procyanidins and anthocyanins in young and aged Prokupac wines toward salivary proteins is investigated via SDS-PAGE and UHPLC-QTOF-MS to determine the differences between the phenolic compounds of red wine in relation to the aging process of wine. SDS-PAGE analysis revealed that procyanidins, flavanol-anthocyanin polymers, and ellagitannins in aged wine have strong affinities for salivary proteins, leading to the formation of insoluble complexes. By contrast, young wine contained predominantly procyanidins with high salivary protein affinity, as well as monomeric flavan-3-ols and anthocyanins, which mainly form soluble aggregates, while polymeric phenolics were less represented. Electrophoretic patterns further showed that seed-derived procyanidins mainly formed insoluble complexes with salivary proteins, whereas skin-derived anthocyanins tended to form soluble ones. The total content of all phenolic compounds quantified by UHPLC-QTOF-MS was 2.5 times higher in young wine than in aged wine, primarily due to the significantly greater abundance of malvidine-3-

Indexed as

aged wineanthocyaninsprocyanidinsProkupacsalivary proteinsyoung wine

Identifiers

PMID40428559
PMCPMC12111099

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.