Evidence map›Paper›PMID 40428517›Full record

ArticleFoods (Basel, Switzerland)2025

Unexpected Cow's Milk Proteins in a "Vegan" Easter Egg as a Cause of Anaphylaxis.

Corinne Bani, Patrizia Restani, Salvatore Tripodi, Francesca Mercogliano, Francesca Colombo, Chiara Di Lorenzo

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Corinne BaniDepartment of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-9736-8746
Patrizia RestaniFaculty of Pharmacy, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-3008-5987
Salvatore TripodiAllergology Service, Policlinico Casilino Hospital, 00169 Rome, Italy.ORCID 0000-0003-2517-3285
Francesca MercoglianoDepartment of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-1785-0437
Francesca ColomboDepartment of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Chiara Di LorenzoDepartment of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-2798-8720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCow's milk is the most frequent cause of food allergies in children, with caseins and β-lactoglobulin being considered the main allergens. Concerningly, numerous international agencies have highlighted a growing risk of allergic reactions in milk-allergic individuals after the consumption of products labelled as "vegan".

objectivesWe describe the case of a 3.5-year-old boy with a history of a food allergy to milk who complained of anaphylactic clinical symptoms after eating a vegan Easter egg. The aim of this study was to confirm the cause of the clinical symptoms, searching for the possible presence of milk proteins in the vegan chocolate.

methodsAn experimental approach based on electrophoretic (SDS-PAGE) and immunoenzymatic techniques (ELISA) was applied.

resultsSDS-PAGE indicated the presence of milk proteins, which was confirmed and quantified via ELISA (3034 ± 115 mg/kg).

conclusionsThe data obtained demonstrate that the severe clinical symptoms were due to the unexpected presence of milk proteins in a vegan product, underlining the critical need for rigorous allergen quality control throughout the food industry.

Indexed as

ELISA assayfood allergymilk proteinsSDS-PAGE

Identifiers

PMID40428517
PMCPMC12110987

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