Evidence map›Paper›PMID 40428385›Full record

ArticleGenes2025

F

Sajjad Toghiani, Samuel E Aggrey, Romdhane Rekaya

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sajjad ToghianiAnimal Genomics and Improvement Laboratory, Agricultural Research Service, USDA, Beltsville, MD 20705, USA.ORCID 0000-0002-5090-728X
Samuel E AggreyInstitute of Bioinformatics, The University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-7550-1681
Romdhane RekayaInstitute of Bioinformatics, The University of Georgia, Athens, GA 30602, USA.ORCID 0000-0003-1545-4331

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesGenomic selection (GS) has improved accuracy compared to traditional methods. However, accuracy tends to plateau beyond a certain marker density. Prioritizing influential SNPs could further enhance the accuracy of GS. The fixation index (F

methodsA trait with heritability of 0.1 and 0.4 was generated under different simulation scenarios (number of QTL, size of SNP windows around QTL, and number of selected SNPs within a QTL region). In total, six simulation scenarios were analyzed. Each scenario was replicated five times. The population comprised 30K animals from the last 2 generations (G9-G10) of a 10-generation (G1-G10) selection process. All animals in G9-10 were genotyped with a 600K SNP panel. F

resultsPrioritizing SNPs using F

conclusionsThe increase in GS accuracy warrants the testing of the algorithm when the number and position of QTL are unknown.

Indexed as

GenomicsPolymorphism, Single NucleotideQuantitative Trait LociSelection, GeneticAnimalsBreedingCattleComputer SimulationGenetic MarkersGenotypeModels, GeneticGenetic MarkersFST prioritizationgenomic selectionhigh-density marker panels

Identifiers

PMID40428385
PMCPMC12111557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.