Evidence map›Paper›PMID 40428375›Full record

ReviewGenes2025

Updates on the Regulatory Framework of Edited Organisms in Brazil: A Molecular Revolution in Brazilian Agribusiness.

Nicolau B da Cunha, Jaim J da Silva Junior, Amanda M M Araújo, Ludmila R de Souza, Michel L Leite, Gabriel da S Medina, Gustavo R Rodriguez, Renan M Dos Anjos, Júlio C M Rodrigues, Fabrício F Costa and 3 more

Abstract readReview
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. CRISPR-Cas Gene Editing Technology in Potato.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nicolau B da CunhaFaculty of Agronomy and Veterinary Medicine (FAV), Campus Darcy Ribeiro, University of Brasilia (UnB), Brasília 70910-970, DF, Brazil.ORCID 0000-0001-5323-4300
Jaim J da Silva JuniorFaculty of Agronomy and Veterinary Medicine (FAV), Campus Darcy Ribeiro, University of Brasilia (UnB), Brasília 70910-970, DF, Brazil.ORCID 0000-0003-0201-3537
Amanda M M AraújoPost-Graduation in Agronomy Program (PPGA), Campus Darcy Ribeiro, University of Brasilia (UnB), Brasília 70910-970, DF, Brazil.
Ludmila R de SouzaPost-Graduation in Agronomy Program (PPGA), Campus Darcy Ribeiro, University of Brasilia (UnB), Brasília 70910-970, DF, Brazil.ORCID 0000-0002-6866-6912
Michel L LeiteGenomic Sciences and Biotechnology Program, Catholic University of Brasilia, Brasília 71966-700, DF, Brazil.ORCID 0000-0002-6291-3716
Gabriel da S MedinaFaculty of Agronomy and Veterinary Medicine (FAV), Campus Darcy Ribeiro, University of Brasilia (UnB), Brasília 70910-970, DF, Brazil.ORCID 0000-0002-5815-6812
Gustavo R RodriguezInstituto de Investigaciones en Ciencias Agrarias de Rosario, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Rosario (IICAR-CONICET-UNR), Campo Experimental Villarino, Zavalla S2125ZAA, Argentina.ORCID 0000-0002-4171-4099
Renan M Dos AnjosPost-Graduation in Molecular Biology Program (PPGMol), Campus Darcy Ribeiro, University of Brasilia (UnB), Brasília 70910-900, DF, Brazil.ORCID 0009-0008-9087-4532
Júlio C M RodriguesEmbrapa Genetic Resources and Biotechnology, PqEB W5 Norte, Brasília 70770-917, DF, Brazil.
Fabrício F CostaCancer Biology and Epigenomics Program, Northwestern University's Feinberg School of Medicine, Chicago, IL 60611, USA.
Simoni C DiasGenomic Sciences and Biotechnology Program, Catholic University of Brasilia, Brasília 71966-700, DF, Brazil.
Elíbio L RechEmbrapa Genetic Resources and Biotechnology, PqEB W5 Norte, Brasília 70770-917, DF, Brazil.ORCID 0000-0001-8588-0673
Giovanni R ViannaEmbrapa Genetic Resources and Biotechnology, PqEB W5 Norte, Brasília 70770-917, DF, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome editing technologies have revolutionized the production of microorganisms, plants, and animals with phenotypes of interest to agriculture. Editing previously sequenced genomes allows for the punctual, discreet, precise, and accurate alteration of DNA for genetic analysis, genotyping, and phenotyping, as well as the production of edited organisms for academic and industrial purposes, among many other objectives. In this context, genome editing technologies have been causing a revolution in Brazilian agriculture. Thanks to the publication of Normative Resolution No. 16 (in Portuguese Resolução Normativa No. 16-RN16) in 2018, Brazilian regulatory authorities have adapted to the new genetic manipulation technologies available to the scientific community. This review aims to describe the effects of updates to the regulatory framework for edited organisms in Brazil and to point out their impacts on research and development of emerging technologies in the Brazilian agricultural sector. The implementation of RN16 rationalized the regulatory aspects regarding the production, manipulation, exploration and commercial release of edited organisms and led to the faster, cheaper and safer obtaining of edited technologies, which are more productive and better adapted to different environmental conditions in Brazil.

Indexed as

AgricultureGene EditingAnimalsBrazilbiotechnological productsedited organismsgenome editing technologiesregulatory framework

Identifiers

PMID40428375
PMCPMC12111335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.