ArticleDiagnostics (Basel, Switzerland)2025
The Clinical and Laboratory Profiles of a Deletional α2-Globin Gene Polyadenylation Signal Sequence (AATAAA > AATA--) [HBA2:c.*93_*94delAA]: The Malaysian Experience.
Norafiza Mohd Yasin, Syahzuwan Hassan, Nur Aisyah Aziz, Faidatul Syazlin Abdul Hamid, Ezalia Esa, Ezzanie Suffya Zulkefli, Rohana Ghazali, Syirah Nazirah Tajuddin, Mohd Nazif Darawi, Yuslina Mat Yusoff and 1 more
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In one paragraphArticle in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Norafiza Mohd YasinHaematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Shah Alam 40170, Selangor, Malaysia.ORCID 0000-0003-4202-2438 Syahzuwan HassanHaematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Shah Alam 40170, Selangor, Malaysia.ORCID 0000-0002-9886-504X Nur Aisyah AzizHaematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Shah Alam 40170, Selangor, Malaysia.
Faidatul Syazlin Abdul HamidHaematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Shah Alam 40170, Selangor, Malaysia.ORCID 0009-0006-8471-7712 Ezalia EsaHaematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Shah Alam 40170, Selangor, Malaysia.
Ezzanie Suffya ZulkefliHaematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Shah Alam 40170, Selangor, Malaysia.ORCID 0000-0003-0270-6034 Rohana GhazaliHaematology Unit, Department of Pathology, Hospital Melaka, Melaka 75400, Malaysia.
Syirah Nazirah TajuddinHaematology Unit, Department of Pathology, Hospital Tuanku Jaafar, Seremban 70300, Negeri Sembilan, Malaysia.
Mohd Nazif DarawiDepartment of Medical Diagnostics, Faculty of Health Sciences, University Selangor, Shah Alam 40000, Selangor, Malaysia.
Yuslina Mat YusoffHaematology Unit, Cancer Research Centre (CaRC), Institute for Medical Research (IMR), National Institute for Health (NIH), Shah Alam 40170, Selangor, Malaysia.
Cornelis L HarteveldLeiden University Medical Centre, 2333 ZA Leiden, The Netherlands.
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Poly A (AATAAA > AATA--) [HBA2:c.*93_*94delAA] is a rare α-variant reported in our population. It is caused by 2 bp deletion (--AA) in the α2 poly A sequence, leading to a significant α-thalassaemia phenotype.
Indexed as
AATA(--AA)Hb H diseasenon-deletional α-thalassaemiapolyadenylation mutation
Identifiers
PMID40428277
PMCPMC12110140
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