Advancing Tissue Engineering Through a Portable Perfusion and Incubation System.

Angie Zhu, Emmett Reid, Tilak Jain, Amatullah Mir, Usmaan Siddiqi, Olivia Dunne, Narutoshi Hibino

Abstract read

In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Dynamic Perfusion and Cell Seeding Density Govern Remodeling and Mechanical Maturation of Bioprinted Collagen Constructs.Gels (Basel, Switzerland) · 2026
Article
The New Frontiers of Artificial Organ Engineering.Bioengineering (Basel, Switzerland) · 2026
Article
3D triply periodic minimal surface gyroid hydrogel scaffolds for soft tissue engineering.Nature communications · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angie ZhuSection of Cardiac Surgery, Department of Surgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.ORCID 0000-0003-4637-721X

Emmett ReidSection of Cardiac Surgery, Department of Surgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.ORCID 0009-0000-2637-0868

Tilak Jain37degrees, 111 North Wabash Ave. Ste. 100, Chicago, IL 60602, USA.

Amatullah MirSection of Cardiac Surgery, Department of Surgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.ORCID 0000-0002-6015-9350

Usmaan SiddiqiSection of Cardiac Surgery, Department of Surgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.

Olivia DunneSection of Cardiac Surgery, Department of Surgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.

Narutoshi HibinoSection of Cardiac Surgery, Department of Surgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perfusion offers unique benefits to tissue-engineered systems, enhancing oxygen and nutrient transport, which improves tissue formation and growth. In this study, we present a novel and integrated portable perfusion system. Weighing < 10 lbs, the system can maintain continuous flow in a standard incubation environment (37 °C, 5% CO

Indexed as

bioreactorbiotransport systemsheart in a boxperfusiontissue engineering

Identifiers

PMID40428173

DOI10.3390/bioengineering12050554

PMCPMC12109021

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.