Cross-Subject Motor Imagery Electroencephalogram Decoding with Domain Generalization.

Decoding motor imagery (MI) electroencephalogram (EEG) signals in the brain-computer interface (BCI) can assist patients in accelerating motor function recovery. To realize the implementation of plug-and-play functionality for MI-BCI applications, cross-subject models are employed to alleviate time-consuming calibration and avoid additional model training for target subjects by utilizing EEG data from source subjects. However, the diversity in data distribution among subjects limits the model's robustness. In this study, we investigate a cross-subject MI-EEG decoding model with domain generalization based on a deep learning neural network that extracts domain-invariant features from source subjects. Firstly, a knowledge distillation framework is adopted to obtain the internally invariant representations based on spectral features fusion. Then, the correlation alignment approach aligns mutually invariant representations between each pair of sub-source domains. In addition, we use distance regularization on two kinds of invariant features to enhance generalizable information. To assess the effectiveness of our approach, experiments are conducted on the BCI Competition IV 2a and the Korean University dataset. The results demonstrate that the proposed model achieves 8.93% and 4.4% accuracy improvements on two datasets, respectively, compared with current state-of-the-art models, confirming that the proposed approach can effectively extract invariant features from source subjects and generalize to the unseen target distribution, hence paving the way for effective implementation of the plug-and-play functionality in MI-BCI applications.