Evidence map›Paper›PMID 40428093›Full record

ReviewBioengineering (Basel, Switzerland)2025

Regulation of Inflammatory Responses by Pulsed Electromagnetic Fields.

Amr Kaadan, Simona Salati, Ruggero Cadossi, Roy Aaron

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Pulsed Electromagnetic Field Therapy Compared to Conventional Mechanical Prophylaxis for Venous Thromboembolism Prophylaxis in The Intensive Care Unit - Rationale and Design for The SOPHIE Trial.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amr KaadanDepartment of Orthopaedic Surgery, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Simona SalatiMedical Division, Igea S.p.A., 41012 Carpi, Italy.ORCID 0000-0002-8072-1128
Ruggero CadossiMedical Division, Igea S.p.A., 41012 Carpi, Italy.
Roy AaronDepartment of Orthopaedic Surgery, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.ORCID 0000-0002-0745-2267

Funding

Miriam Hospital N/A
6 · The paper itself

Abstract

Pulsed Electromagnetic Field (PEMF) therapy has been shown to have substantial suppressive effects on inflammation and is a promising treatment for the modulation of inflammation. Several in vitro and in vivo studies have shown that PEMFs profoundly suppress inflammatory pathways, such as the NF-κB and MAPK signaling pathways, by lowering cytokine levels and improving extracellular matrix synthesis. This review describes studies, ranging from in vitro to clinical, that investigate the lesser-known roles of PEMF in the modulation of inflammation in soft tissue wound, cartilage, and joint healing, alongside angiogenesis. Mechanistically, PEMFs act via adenosine receptors, specifically A

Indexed as

angiogenesiscartilagediabetic wound healinginflammationpulsed electromagnetic fieldsvenous ulcerswound healing

Identifiers

PMID40428093
PMCPMC12109083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.