Evidence map›Paper›PMID 40427731›Full record

ArticleBiology2025

Exploring Tumor Cell-Platelet Biochemical Interactions by Dielectric Measurements of Blood: A Potential Target for Tumor Detection and Staging.

Annamaria Russo, Ester Tellone, Francesco Farsaci

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Annamaria RussoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0009-0008-9636-519X
Ester TelloneDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0003-2379-3392
Francesco FarsaciDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper aims to investigate the dielectric properties of blood for tumor detection and staging. The application of complex thermodynamic models and the study of the trend over time of some thermodynamic functions have allowed us to highlight the generation of displacement currents caused by changes in charge, i.e., by the activation and consequent accumulation of platelets on migrating tumor cells. Although few studies exist to date in this regard, the technique used has provided promising results, especially in terms of building a database. In this context, the evaluation of the dielectric parameters of healthy and cancerous blood can be exploited for the staging of cancer. The main advantages of this method include easy application, non-invasiveness, low cost, and online monitoring.

Indexed as

cancercirculating tumor cellsnon-equilibrium thermodynamicsplateletstumor staging

Identifiers

PMID40427731
PMCPMC12108633

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.