High-Throughput Analysis of the Flagella FliK-Dependent Surfaceome and Secretome in

Carine Mouawad, Mireille Kallassy Awad, Carine Rodrigues-Machado, Céline Henry, Vincent Sanchis-Borja, Laure El Chamy

Abstract read

In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Paradigm shift formBio · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carine MouawadUnité de Recherche Environnement, Génomique et Protéomique, Faculté des Sciences, Université Saint-Joseph de Beyrouth-Liban, Mar Roukos, Mkalles, Beirut 1107 2050, Lebanon.

Mireille Kallassy AwadUnité de Recherche Environnement, Génomique et Protéomique, Faculté des Sciences, Université Saint-Joseph de Beyrouth-Liban, Mar Roukos, Mkalles, Beirut 1107 2050, Lebanon.ORCID 0000-0003-1489-8686

Carine Rodrigues-MachadoUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, PAPPSO, 78350 Jouy-en-Josas, France.ORCID 0000-0003-3675-6267

Céline HenryUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, PAPPSO, 78350 Jouy-en-Josas, France.ORCID 0000-0002-2355-1791

Vincent Sanchis-BorjaUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350 Jouy-en-Josas, France.ORCID 0000-0001-9492-3866

Laure El ChamyUnité de Recherche Environnement, Génomique et Protéomique, Faculté des Sciences, Université Saint-Joseph de Beyrouth-Liban, Mar Roukos, Mkalles, Beirut 1107 2050, Lebanon.

Funding

Research Council of the Saint-Joseph University of Beirut (FS119 and FS139), the Institut National de la Recherche pour l'agriculture, l'alimentation et l'environement (INRAE), CEDRE program (42229SF), SAFAR program FS119-FS139

6 · The paper itself

Abstract

Bacterial pathogens employ multiple strategies to invade and damage host tissues while evading immune defenses. Recent studies highlight flagella as crucial contributors to bacterial virulence, not only by facilitating motility, but also by regulating the secretion of virulence factors. However, the role of the flagella-dependent secretome remains largely unexplored. We have recently shown that FliK, a key regulator that defines substrate specificity in the flagellar export apparatus, is essential for the resistance of

Indexed as

antimicrobial peptides resistanceBacillus thuringiensisflagellaFliKsecretomesurfaceomevirulence

Identifiers

PMID40427714

DOI10.3390/biology14050525

PMCPMC12109265

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.