Evidence map›Paper›PMID 40427657›Full record

ArticleBiology2025

Pathway-Specific Insights into Colorectal Cancer Through Comprehensive Multi-Omics Data Integration.

Tayyip Karaman, Sinem Oktem Okullu, Günseli Bayram Akçapınar, Osman Ugur Sezerman

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tayyip KaramanDepartment of Medical Biotechnology, Institute of Health Science, Acibadem Mehmet Ali Aydinlar University, Atasehir, Istanbul 34752, Turkey.ORCID 0000-0003-1941-3019
Sinem Oktem OkulluDepartment of Medical Microbiology, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Atasehir, Istanbul 34752, Turkey.ORCID 0000-0002-2255-0930
Günseli Bayram AkçapınarDepartment of Medical Biotechnology, Institute of Health Science, Acibadem Mehmet Ali Aydinlar University, Atasehir, Istanbul 34752, Turkey.
Osman Ugur SezermanDepartment of Biostatistics and Medical Informatics, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Atasehir, Istanbul 34752, Turkey.

Funding

Scientific and Technological Research Council of Turkey 118C039
6 · The paper itself

Abstract

Thousands of biomarkers have been discovered to solve the mechanisms of cancer, but dynamic alterations in the parameters that affect cancer progression cause complex disease status. Therefore, it is essential when dealing with cancer to analyze all parameters, including pathway information, to understand the disease mechanism of action. In our study, we applied multi-omics data integration for microbiome, transcriptome, and microbial pathway datasets obtained from colorectal cancer patients. The

Indexed as

colorectal cancermetabolic pathwaysmicrobiomemulti-omics data integrationtranscriptome

Identifiers

PMID40427657
PMCPMC12109357

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.