Evidence map›Paper›PMID 40427604›Full record

ArticleBiomolecules2025

Vitamin D and Retinoic Acid Require Protein Kinase C Activity and Reactive Oxygen Species as Opposing Signals Regulating

Pablo A Iglesias González, Consuelo Mori, Ángel G Valdivieso, Tomás A Santa Coloma

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Multi-omics characterization of a GPRC5AJournal of translational medicine · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pablo A Iglesias GonzálezLaboratory of Cellular and Molecular Biology, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina, Alicia Moreau de Justo 1600, Buenos Aires 1107, Argentina.
Consuelo MoriLaboratory of Cellular and Molecular Biology, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina, Alicia Moreau de Justo 1600, Buenos Aires 1107, Argentina.
Ángel G ValdiviesoLaboratory of Cellular and Molecular Biology, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina, Alicia Moreau de Justo 1600, Buenos Aires 1107, Argentina.ORCID 0000-0002-7928-4880
Tomás A Santa ColomaLaboratory of Cellular and Molecular Biology, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina, Alicia Moreau de Justo 1600, Buenos Aires 1107, Argentina.ORCID 0000-0002-3266-1095

Funding

Agencia Nacional de Promoción Científica y Tecnológica (ANPCYT), Argentina PICT 2018-77204429 , PICT 2020 A-03854Consejo Nacional de Investigaciones Científicas y Técnicas PIP 2015-2017 11220150100227CO, PIP 2022-2024 11220210100990CO
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colonic NeoplasmsProtein Kinase CReactive Oxygen SpeciesReceptors, G-Protein-CoupledTretinoinVitamin DCaco-2 CellsCell Line, TumorGene Expression Regulation, NeoplasticHumansSignal TransductionGPRC5A protein, humanProtein Kinase CReactive Oxygen SpeciesReceptors, G-Protein-CoupledTretinoinVitamin DATRAcancerchemopreventionGPRC5APKCretinoic acidROSvitamin D

Identifiers

PMID40427604
PMCPMC12108993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.