Evidence map›Paper›PMID 40427577›Full record

ReviewBiomolecules2025

PlastiCRISPR: Genome Editing-Based Plastic Waste Management with Implications in Polyethylene Terephthalate (PET) Degradation.

Puja Palit, Maya Minkara, Maisha Abida, Safa Marwa, Chandrima Sen, Ayan Roy, Md Ridoan Pasha, Paulraj Selvakumar Mosae, Ayan Saha, Jannatul Ferdoush

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Puja PalitDepartment of Biological Sciences, Asian University for Women, Chittagong 4000, Bangladesh.ORCID 0009-0005-6486-6692
Maya MinkaraDepartment of Biology, Geology, and Environmental Science, University of Tennessee at Chattanooga, 615 McCallie Ave, Chattanooga, TN 37403, USA.ORCID 0009-0009-7169-5632
Maisha AbidaDepartment of Biological Sciences, Asian University for Women, Chittagong 4000, Bangladesh.
Safa MarwaDepartment of Biological Sciences, Asian University for Women, Chittagong 4000, Bangladesh.
Chandrima SenDepartment of Biological Sciences, Asian University for Women, Chittagong 4000, Bangladesh.ORCID 0009-0008-6322-4315
Ayan RoyDepartment of Biological Sciences, Asian University for Women, Chittagong 4000, Bangladesh.
Md Ridoan PashaDepartment of Physiology, Biochemistry, and Pharmacology, Chattogram Veterinary and Animal Sciences University, Khulshi, Chattogram 4225, Bangladesh.ORCID 0000-0001-6697-3057
Paulraj Selvakumar MosaeDepartment of Environmental Sciences, Asian University for Women, Chittagong 4000, Bangladesh.ORCID 0000-0002-8712-1168
Ayan SahaDepartment of Biological Sciences, Asian University for Women, Chittagong 4000, Bangladesh.ORCID 0000-0003-1101-8372
Jannatul FerdoushDepartment of Biology, Geology, and Environmental Science, University of Tennessee at Chattanooga, 615 McCallie Ave, Chattanooga, TN 37403, USA.ORCID 0000-0001-5925-5057

Funding

University of Tennessee at Chattanooga Start-up fund
6 · The paper itself

Abstract

Plastic pollution has become a significant environmental issue worldwide, with global plastic production expected to reach 1800 million tons by 2050. One of the most commonly used plastics in the world is polyethylene terephthalate (PET), a synthetic polymer that is extremely durable but difficult to degrade. Thus, PET is dangerous to human health. To address this crisis, innovative approaches are being developed, including genome editing technologies. One of the recently advanced genome editing technologies is PlastiCRISPR, a novel concept that applies CRISPR-based genome editing to transform plastic waste management. PlastiCRISPR utilizes microorganisms to degrade plastic, generating valuable bioproducts like biofuels and biochemicals. Thus, this technology offers a sustainable solution because of its simple design, adequacy, and low cost, which can be integrated into existing waste management systems. Importantly, this review focuses on the PlastiCRISPR-based management of PET because it could drastically lower plastic waste, sustain natural resources by decreasing the requirement for plastic production, minimize energy intake, etc. Overall, this review provides an overview of the principles, applications, challenges, and future prospects of PlastiCRISPR in combating plastic pollution and shaping a more sustainable future.

Indexed as

Gene EditingPlasticsPolyethylene TerephthalatesWaste ManagementBiodegradation, EnvironmentalCRISPR-Cas SystemsHumansPlasticsPolyethylene Terephthalatesbiodegradationbioplastic productionbiotechnologyCRISPR-Cas9environmental sustainabilitygenome editingmicroorganismsPlastiCRISPR

Identifiers

PMID40427577
PMCPMC12109117

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.