Evidence map›Paper›PMID 40427523›Full record

ArticleBiomolecules2025

HNF4α-Mediated LINC02560 Promotes Papillary Thyroid Carcinoma Progression by Targeting the miR-505-5p/PDE4C Axis.

Yongcheng Su, Beibei Xu, Chunyi Gao, Wenbin Pei, Miaomiao Ma, Wenqing Zhang, Tianhui Hu, Fuxing Zhang, Shaoliang Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yongcheng SuDepartment of Traditional Chinese Medicine and Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen 361102, China.
Beibei XuInstitute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Chunyi GaoDepartment of Traditional Chinese Medicine and Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen 361102, China.
Wenbin PeiDepartment of Traditional Chinese Medicine and Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen 361102, China.
Miaomiao MaDepartment of Traditional Chinese Medicine and Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen 361102, China.
Wenqing ZhangDepartment of Traditional Chinese Medicine and Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen 361102, China.
Tianhui HuDepartment of Traditional Chinese Medicine and Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen 361102, China.ORCID 0000-0003-3998-5145
Fuxing ZhangDepartment of General Surgery, The First Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China.
Shaoliang ZhangDepartment of Traditional Chinese Medicine and Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen 361102, China.

Funding

National Natural Science Foundation of China 82472651,82204424Natural Science Foundation of Fujian Province of China 2024R1001002Scientific Research Foundation of Xiang An Biomedicine Laboratory 2023XAKJ0101023Shenzhen Science and Technology Program JCY20220530143406015
6 · The paper itself

Abstract

Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid malignancy, and its progression is closely associated with patient outcomes. This study investigated the role of the long non-coding RNA

Indexed as

Cyclic Nucleotide Phosphodiesterases, Type 4Hepatocyte Nuclear Factor 4MicroRNAsRNA, Long NoncodingThyroid Cancer, PapillaryThyroid NeoplasmsCell Line, TumorCell MovementCell ProliferationDisease ProgressionEpithelial-Mesenchymal TransitionFemaleGene Expression Regulation, NeoplasticHumansMaleSignal TransductionCyclic Nucleotide Phosphodiesterases, Type 4Hepatocyte Nuclear Factor 4HNF4A protein, humanMicroRNAsRNA, Long Noncodinggrowth and metastasisHNF4αLINC02560miR-505-5pPDE4CPTC

Identifiers

PMID40427523
PMCPMC12108885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.