Evidence map›Paper›PMID 40427512›Full record

ArticleBiomolecules2025

Field-Effect Transistor Based on Nanocrystalline Graphite for DNA Immobilization.

Bianca Adiaconita, Eugen Chiriac, Tiberiu Burinaru, Catalin Marculescu, Cristina Pachiu, Oana Brincoveanu, Octavian Simionescu, Marioara Avram

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bianca AdiaconitaNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.ORCID 0000-0003-3784-0807
Eugen ChiriacNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.ORCID 0000-0001-9048-1853
Tiberiu BurinaruNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.
Catalin MarculescuNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.ORCID 0000-0001-7177-1521
Cristina PachiuNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.ORCID 0000-0003-1799-5158
Oana BrincoveanuNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.
Octavian SimionescuNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.ORCID 0000-0001-5827-503X
Marioara AvramNational Institute for Research and Development in Microtechnologies-IMT Bucharest, 126A Erou Iancu, Nicolae, 077190 Voluntari, Ilfov, Romania.ORCID 0000-0002-4126-7401

Funding

European Regional Development Fund under the Program for Intelligent Growth, Digitization, and Financial Instruments project "National Platform for Semiconductor Technologies", contract no. G 2024-85828/390008/27.11.2024, SMIS code 304244Romanian Ministry of Research, PNCDI - UEFISCDI, in the "Core program from the Research, Development and Innovation National Plan 2022-2027", conducted with MCID aid contract no. 8N/2023, project no. 2307
6 · The paper itself

Abstract

In recent years, field-effect transistors (FETs) based on graphene have attracted significant interest due to their unique electrical properties and their potential for biosensing and molecular detection applications. This study uses FETs with a nanocrystalline graphite (NCG) channel to detect DNA nucleobases. The exceptional electronic properties of NCG, and its high surface area, enable strong π-π stacking interactions with DNA nucleobases, promoting efficient adsorption and stabilization of the biomolecules. The direct attachment of nucleobases to the NCG channel leads to substantial changes in the device's electrical characteristics, which can be measured in real time to assess DNA binding and sequence recognition. This method enables highly sensitive, label-free DNA detection, opening up new possibilities for rapid genetic analysis and diagnostics. Understanding the interactions between DNA nucleobases and graphene-based materials is crucial for advancing genetic research and biotechnology, paving the way for more accurate and efficient diagnostic tools.

Indexed as

Biosensing TechniquesDNAGraphiteImmobilized Nucleic AcidsNanoparticlesTransistors, ElectronicDNAGraphiteImmobilized Nucleic AcidsDirac pointDNA technologiesfield-effect transistorgraphene-related materialmobilitynucleobase

Identifiers

PMID40427512
PMCPMC12108642

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.