Evidence map›Paper›PMID 40427457›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Aster-B Modulates Oxidative Stress Responses and Carotenoid Distribution in ARPE-19 Cells.

Vidya Gopakumar, Johannes von Lintig

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vidya GopakumarDepartment of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0009-0005-4079-0152
Johannes von LintigDepartment of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0002-2079-2143

Funding

Carotinoids in VisionR01EY020551 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI VON LINTIG, JOHANNES FRIEDRICH · 2011 to 2024
$4.8M
STRA6 and Ocular Vitamin A HomeostasisR01EY028121 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI Johannes Friedrich von Lintig · 2018 to 2026
$4.3M
NEI NIH HHS R01 EY020551NEI NIH HHS R01 EY028121NIH HHS 1C06EY020551-24A1
6 · The paper itself

Abstract

Lipid metabolism and oxidative stress are major contributors to ocular diseases, including drusen formation and photoreceptor damage. Aster-B, encoded by

Indexed as

Aster-BcarotenoidscholesterolCRISPR/dCas9oxidative stressretinal pigment epithelium

Identifiers

PMID40427457
PMCPMC12108295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.