Evidence map›Paper›PMID 40427456›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Red Wine Grape Pomace Restores Gut Barrier Function and Improves Survival in Diet-Induced Ischemic Heart Disease.

Katherine Rivera, Leticia González, Laura Parra, Juan E Oyarzún, Alina Concepción-Alvarez, Adriano Costa de Camargo, Raquel Bridi, Attilio Rigotti, Marcelo E Andia

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katherine RiveraDoctoral Program in Medical Sciences, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.ORCID 0000-0003-1850-5560
Leticia GonzálezRadiology Department and Biomedical Imaging Center, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0000-0002-0589-6884
Laura ParraDoctoral Program in Medical Sciences, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.
Juan E OyarzúnRadiology Department and Biomedical Imaging Center, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
Alina Concepción-AlvarezNutrition and Food Technology Institute, University of Chile, Santiago 7830490, Chile.ORCID 0000-0001-6161-5998
Adriano Costa de CamargoNutrition and Food Technology Institute, University of Chile, Santiago 7830490, Chile.ORCID 0000-0001-9404-1193
Raquel BridiDepartamento de Química Farmacológica y Toxicológica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8380494, Chile.ORCID 0000-0002-3891-5770
Attilio RigottiCentro de Nutrición Molecular y Enfermedades Crónicas, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago 8331010, Chile.
Marcelo E AndiaRadiology Department and Biomedical Imaging Center, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0000-0002-1251-5832

Funding

Agencia Nacional de Investigación y Desarrollo Beca Doctorado Nacional 21201346Agencia Nacional de Investigación y Desarrollo Beca Doctorado Nacional 21230932Agencia Nacional de Investigación y Desarrollo FONDECYT Regular 1220922Agencia Nacional de Investigación y Desarrollo Proyecto FONDECYT Postdoctorado2023 3230777Millennium Science Initiative Program ICN2021_04
6 · The paper itself

Abstract

Red wine grape pomace (RWGP), a winemaking by-product rich in phenolics, flavonoids, and dietary fiber, has shown promise in mitigating cardiovascular disease (CVD), however, its mechanisms of action remain incompletely understood. This study comprehensively profiled the phenolic composition of RWGP-including free, esterified, etherified, and insoluble-bound fractions-and evaluated the effects of RWGP dietary supplementation on gut barrier integrity, inflammation, oxidative stress, and survival in SR-B1

Indexed as

endotoxemiagut–heart axisgut permeabilityischemic heart diseasephenolic compoundsred wine grape pomace

Identifiers

PMID40427456
PMCPMC12108506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.