Evidence map›Paper›PMID 40427312›Full record

ArticleAnimals : an open access journal from MDPI2025

Plasma Hormone and Metabolomics Identifies Metabolic Pathways Associated with Growth Rate of Dezhou Donkeys.

Liyuan Wang, Tong Li, Qiugang Ma, Honglei Qu, Changfa Wang, Wenqiang Liu, Wenqiong Chai

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Liyuan WangLiaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng 252000, China.
Tong LiLiaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng 252000, China.
Qiugang MaState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-7260-3765
Honglei QuState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Changfa WangLiaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng 252000, China.ORCID 0000-0002-5186-1703
Wenqiang LiuLiaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng 252000, China.ORCID 0000-0001-5028-0467
Wenqiong ChaiLiaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng 252000, China.ORCID 0000-0003-2805-824X

Funding

National Key R&D Program of China 2023YFD1302000National Natural Science Foundation of China 32102531Shandong Province Natural Science Foundation ZR2023MC209
6 · The paper itself

Abstract

backgroundThe growth traits of donkeys from the same farm under the same feeding conditions often vary.

methodsIn this study, Plasma hormone level and LC-MS-based metabolomics was used to identify the metabolic pathways and the key metabolites associated with the growth rate of Dezhou donkeys.

resultsThe level of IGF-1 in the SG was significantly higher than that in the FG. The differentially abundant metabolites were related mainly to lipid metabolism, in which arachidonic acid metabolism, linoleic acid metabolism and steroid hormone biosynthesis played key roles. The main differentially abundant metabolites 2,3-dinor-8-iso-PGF2α, 11-DH-TXB2, 8(R)-HPETE, PGJ2, c9, t11-CLA, 12,13-DHOME, 9,10-DHOME, 9(10)-EpOME, 13-HPODE, DHEAS, testosterone, and corticosterone played important roles in metabolic homeostasis and affected the adaptation of donkeys to cold environments.

conclusionsThe present study revealed that the growth rate of donkeys is mainly influenced by their adaptation to the environment, providing a more in-depth study on the relationship between plasma metabolomics and growth rate in donkeys.

Indexed as

donkeygrowth traithormonesmetabolomics

Identifiers

PMID40427312
PMCPMC12108408

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