Evidence map›Paper›PMID 40427221›Full record

ArticleCancers2025

From Intensification to Optimization: Balancing Efficacy, Safety, and Costs in High-Risk Localized Soft Tissue Sarcomas.

Bruno Fuchs, Georg Schelling, Christoph Glanzmann, Gabriela Studer, On Behalf Of The Swiss Sarcoma Network

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bruno FuchsFaculty of Health Sciences & Medicine, University Lucerne, Frohburgstrasse 3, 6002 Luzern, Switzerland.ORCID 0000-0001-6453-3947
Georg SchellingSarcoma Service, Department of Orthopedics and Trauma, Sarcoma Center, LUKS University Hospital, 6000 Luzern, Switzerland.
Christoph GlanzmannSarcoma Service, Department of Radiation Oncology, Sarcoma Center, LUKS University Hospital, 6000 Luzern, Switzerland.
Gabriela StuderFaculty of Health Sciences & Medicine, University Lucerne, Frohburgstrasse 3, 6002 Luzern, Switzerland.ORCID 0000-0001-8780-7701
On Behalf Of The Swiss Sarcoma Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

high-risk sarcoma managementPD-1 checkpoint inhibitionreal-world evidencesoft tissue sarcomasurvival outcomessystemic therapytherapy de-intensificationtreatment toxicityultra-hypofractionated preoperative radiotherapy (uhpRT)value-based healthcare

Identifiers

PMID40427221
PMCPMC12109959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.