Evidence map›Paper›PMID 40427180›Full record

ReviewCancers2025

Impact of Pain Education on Pain Relief in Oncological Patients: A Narrative Review of Systematic Reviews and Meta-Analyses.

Erika Galietta, Costanza M Donati, Alberto Bazzocchi, Rebecca Sassi, Arina A Zamfir, Renée Hovenier, Clemens Bos, Nikki Hendriks, Martijn F Boomsma, Mira Huhtala and 5 more

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Erika GaliettaDepartment of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Costanza M DonatiDepartment of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Alberto BazzocchiDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Rebecca SassiDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Arina A ZamfirRadiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0009-0008-9966-6342
Renée HovenierDivision of Imaging and Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.ORCID 0009-0004-0858-7472
Clemens BosDivision of Imaging and Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.ORCID 0000-0002-9246-3242
Nikki HendriksDepartment of Radiology, Isala Hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.ORCID 0009-0001-7109-7044
Martijn F BoomsmaDepartment of Radiology, Isala Hospital, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.ORCID 0000-0002-7878-0970
Mira HuhtalaDepartment of Oncology and Palliative Center, Turku University Hospital, University of Turku, 20520 Turku, Finland.ORCID 0000-0002-4771-8998
Roberto Blanco SequeirosResearch Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, 90014 Oulu, Finland.
Holger GrüllInstitute of Diagnostic and Interventional Radiology, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50923 Cologne, Germany.ORCID 0000-0002-0993-9300
Simone FerdinandusDepartment of Radiation Oncology, Cyberknife and Radiotherapy, Faculty of Medicine and University Hospital Cologne, 50931 Cologne, Germany.
Helena M VerkooijenDivision of Imaging and Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
Alessio G MorgantiDepartment of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.ORCID 0000-0001-9793-3410

Funding

European Union's Horizon 2020 825859
6 · The paper itself

Abstract

Pain is a complex and burdensome symptom frequently experienced by oncological patients. Despite increased attention from healthcare providers and novel approaches, pain remains undertreated and prevalent in this patient population. Programs of patient education about pain (pain education, PE) have been proposed as a potential method to enhance pain management. However, the effectiveness of such programs and their impact on pain relief have shown variable results across studies. In this narrative review, we analyzed existing systematic reviews and meta-analyses on PE in oncological patients. A comprehensive literature search was conducted using PubMed, Scopus, and the Cochrane Library databases, following established guidelines. Studies meeting the selection criteria were selected and analyzed to evaluate the effectiveness of PE interventions. A total of nine publications, comprising six systematic reviews and three meta-analyses, were included. Across various clinical settings (inpatient and outpatient), the impact of pain education (PE) on pain intensity showed considerable variability: some reviews reported significant reductions, while others observed minimal or no effects. In contrast, PE consistently improved patients' knowledge about pain and adherence to medication. However, the available evidence did not demonstrate significant improvements in quality of life. The observed heterogeneity in the results of pain relief outcomes could be attributed to the various types of pain analyzed and the diversity of clinical settings evaluated. Furthermore, differences in study designs, comprising the inclusion of non-randomized studies, contributed to the variability in findings. It remains unclear whether the effectiveness of PE is solely attributed to the educational content or if the attention provided to patients during the intervention partly explains the effect.

Indexed as

cancer painmedication adherencemeta-analysisnarrative reviewpain educationpain managementpatient educationquality of lifesystematic review

Identifiers

PMID40427180
PMCPMC12110527

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.