Evidence map›Paper›PMID 40427178›Full record

ArticleCancers2025

High

Ling Cai, Thomas J Rogers, Reza Mousavi Jafarabad, Hieu Vu, Chendong Yang, Nicole Novaresi, Ana Galán-Cobo, Luc Girard, Edwin J Ostrin, Johannes F Fahrmann and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. International journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ling CaiChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-9057-2998
Thomas J RogersChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Reza Mousavi JafarabadQuantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Hieu VuChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Chendong YangChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Nicole NovaresiDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-7890-4382
Ana Galán-CoboDepartment of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-0988-1823
Luc GirardHamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Edwin J OstrinDepartment of General Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-4538-6539
Johannes F FahrmannDepartment of Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Jiyeon KimDepartments of Urology and Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA.
John V HeymachDepartment of Thoracic and Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kathryn A O'DonnellSimmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Guanghua XiaoQuantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Yang XieQuantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ralph J DeBerardinisChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-2705-7432
John D MinnaSimmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-7776-0767

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Kathryn Ann O'Donnell · 2010 to 2026
$53.7M
Metabolic Regulators of Tumor Growth and ProgressionR35CA220449 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI RALPH J DEBERARDINIS · 2017 to 2026
$9.4M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeffrey M Zigman · 2022 to 2026
$7.4M
Construction of A Lung Cancer Preclinical Model Cross-comparison PlatformR01CA285336 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Ling Cai · 2024 to 2026
$3.1M
Novel computational approaches to predict drug response and combination effectsR35GM136375 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI XIE, YANG · 2020 to 2024
$2.0M
The role of translation initiation factor eIF5B in lung cancer pathogenesisR01CA273585 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Kathryn Ann O'Donnell · 2023 to 2026
$1.9M
Uncovering Oncogenotype-specific Vulnerabilities in Lung cancerR37CA285640 · NCI · YALE UNIVERSITY · PI Jiyeon Kim · 2024 to 2026
$1.8M
Developing novel algorithms for spatial molecular profiling technologiesR01GM141519 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI XIAO, GUANGHUA · 2021 to 2024
$1.4M
Targeting a Kynurenine-Driven Autocrine Loop to Block Triple-Negative Breast Cancer MetastasisK00CA212230 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI ROGERS, THOMAS J · 2017 to 2020
$326k
CPRIT RP180805CPRIT RP190107CPRIT RP200327CPRIT RP250391NCI NIH HHS K00CA212230NCI NIH HHS P30 CA142543NCI NIH HHS P50CA70907NCI NIH HHS R01 CA273585NCI NIH HHS R01CA273585NCI NIH HHS R01 CA285336NCI NIH HHS R01CA285336NCI NIH HHS R35 CA220449NCI NIH HHS R35CA220449NCI NIH HHS R37CA285640NIDDK NIH HHS P30 DK127984NIGMS NIH HHS R01 GM141519NIGMS NIH HHS R35GM136375V Foundation T2021-011
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

immune suppressionKEAP1KYNUkynureninasekynurenine pathwaylung adenocarcinomamouse model limitationsNAD metabolismprognostic biomarkerSTK11tryptophan catabolism

Identifiers

PMID40427178
PMCPMC12109616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.