Evidence map›Paper›PMID 40427126›Full record

ArticleCancers2025

The Use of Mutational Signatures to Decipher the Inter-Relationship of Reactive Oxygen Species with Homologous Recombination and Non-Homologous End-Joining Deficiencies as Well as Their Effects on APOBEC Mutagenesis in Breast Cancer.

Amir Farmanbar, Robert Kneller, Sanaz Firouzi

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amir FarmanbarDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639, Japan.
Robert KnellerResearch Center for Advanced Science and Technology, University of Tokyo, Tokyo 153-8904, Japan.
Sanaz FirouziDepartment of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639, Japan.

Funding

Japan Society for the Promotion of Science 17K15044Otsuka Toshimi Scholarship Foundation NATokyo Biochemical Research Foundation TBRF-RF 170-104
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

activation-induced deaminase/apolipoprotein B mRNA editing enzyme catalytic polypeptide-likeAID/APOBECBRCA1BRCA2breast cancerDNA damagehomologous recombination deficiencyHRDmicrosatellite instabilityMSImutational signatureNHEJnon-homologous end joiningreactive oxygen speciesROSTMBtumor mutational burden

Identifiers

PMID40427126
PMCPMC12110613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.