Evidence map›Paper›PMID 40427048›Full record

ReviewBiomedicines2025

Advances in the Treatment of Acute Myeloid Leukemia: Implications for Low- and Middle-Income Countries.

Michelle Morcos-Sandino, Sofia Isabel Quezada-Ramírez, Andrés Gómez-De León

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle Morcos-SandinoHematology Service, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León (UANL), Av. Madero y Gonzalitos S/N, Mitras Centro, Monterrey ZC 64460, Nuevo León, Mexico.ORCID 0000-0002-9301-0106
Sofia Isabel Quezada-RamírezHematology Service, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León (UANL), Av. Madero y Gonzalitos S/N, Mitras Centro, Monterrey ZC 64460, Nuevo León, Mexico.ORCID 0000-0002-4732-3013
Andrés Gómez-De LeónHematology Service, Facultad de Medicina y Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León (UANL), Av. Madero y Gonzalitos S/N, Mitras Centro, Monterrey ZC 64460, Nuevo León, Mexico.ORCID 0000-0001-6904-9345

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemia (AML) presents a significant global health challenge due to its aggressive behavior and mortality rates. Traditionally, AML treatment has relied on intensive chemotherapy-anthracyclines and cytarabine. However, recent breakthroughs in targeted therapies are transforming clinical practices. This review examines current treatment strategies, including breakthrough therapies. Also, a global perspective on AML management includes the disparity in treatment availability, particularly the difficulties faced by low- and middle-income countries due to the high cost and restricted access to novel therapies.

Indexed as

acute myeloid leukemiaBLC-2 InhibitorFLT3 inhibitorshypomethylatingIDH inhibitorsintensive chemotherapynewly diagnosedrelapsed or refractory

Identifiers

PMID40427048
PMCPMC12109363

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.