Evidence map›Paper›PMID 40426994›Full record

ArticleBiomedicines2025

Cannabidiol-Loaded Retinal Organoid-Derived Extracellular Vesicles Protect Oxidatively Stressed ARPE-19 Cells.

Peggy Arthur, Sangeetha Kandoi, Anil Kalvala, Breana Boirie, Aakash Nathani, Mounika Aare, Santanu Bhattacharya, Tanmay Kulkarni, Li Sun, Deepak A Lamba and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Peggy ArthurCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.ORCID 0000-0002-6225-2639
Sangeetha KandoiDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0001-8346-8642
Anil KalvalaCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.
Breana BoirieCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.
Aakash NathaniCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.ORCID 0000-0003-1852-6548
Mounika AareCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.ORCID 0000-0001-7809-4682
Santanu BhattacharyaDepartment of Biochemistry and Molecular Biology, Mayo College of Medicine and Science, Jacksonville, FL 32224, USA.ORCID 0000-0003-3579-4317
Tanmay KulkarniDepartment of Biochemistry and Molecular Biology, Mayo College of Medicine and Science, Jacksonville, FL 32224, USA.ORCID 0000-0002-9194-2460
Li SunDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Tallahassee, FL 32310, USA.ORCID 0000-0001-8228-7487
Deepak A LambaDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-2811-307X
Yan LiDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Tallahassee, FL 32310, USA.ORCID 0000-0002-5938-8519
Mandip SinghCollege of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA.ORCID 0000-0001-9192-8143

Funding

Research Project-3: Effectiveness of an eHealth intervention for uptake of cervical cancer screening in Hispanic womenU54MD007582 · NIMHD · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI KARAM F.A. SOLIMAN · 2019 to 2026
$28.1M
Recruitment and HiringG12MD007582 · NIMHD · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI SOLIMAN, KARAM F.A. · 2012 to 2017
$16.0M
Engineering Extracellular Vesicles of Human Brain Organoids for Stroke TherapyR01NS125016 · NINDS · FLORIDA STATE UNIVERSITY · PI Yan Li · 2022 to 2026
$1.8M
Exosomal Based micro RNA delivery for Resistant Lung CancerR16GM149462 · NIGMS · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI Mandip Singh Sachdeva · 2023 to 2026
$592k
National Institute of Health 5R16GM149462-01NIGMS NIH HHS R16 GM149462NIH HHS R01NS125016NIMHD NIH HHS G12 MD007582NIMHD NIH HHS U54 MD007582NINDS NIH HHS R01 NS125016
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AMPKARPE-19 cellscannabinoidextracellular vesiclesoxidative stressretinal organoidssmall RNA profiling

Identifiers

PMID40426994
PMCPMC12108686

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.