Evidence map›Paper›PMID 40426970›Full record

ArticleBiomedicines2025

Reduced Expression of UPRmt Proteins HSP10, HSP60, HTRA2, OMA1, SPG7, and YME1L Is Associated with Accelerated Heart Failure in Humans.

Petra Bakovic, Vid Mirosevic, Tomo Svagusa, Ana Sepac, Ana Kulic, Davor Milicic, Hrvoje Gasparovic, Igor Rudez, Marjan Urlic, Suncana Sikiric and 13 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Chaperonin in health and disease.Molecular biomedicine · 2026
    Review
  4. Recent insights into HSP70: proteostasis and beyond.Frontiers in molecular biosciences · 2026
    Review
  5. Review
  6. Review
  7. UPRmt-regulated mitokines: novel strategies for myocardial injury repair.Frontiers in cell and developmental biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Petra BakovicDepartment of Pathophysiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Vid MirosevicDepartment of Pathophysiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0003-1966-4731
Tomo SvagusaDepartment of Cardiovascular Diseases, Dubrava Clinical Hospital, 10000 Zagreb, Croatia.ORCID 0000-0002-2036-1239
Ana SepacDepartment of Pathology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Ana KulicDepartment of Oncology, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-0176-1886
Davor MilicicSchool of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Hrvoje GasparovicDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Igor RudezDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-7735-6721
Marjan UrlicDepartment of Cardiac Surgery, University Hospital Center Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0003-0741-9333
Suncana SikiricDepartment of Pathology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Sven SeiwerthDepartment of Pathology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Drazen BelinaDepartment of Cardiac Surgery, University Hospital Center Zagreb, 10000 Zagreb, Croatia.
Matija BakosDepartment of Pediatrics, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-8316-2034
Monika Karija VlahovicDNA Laboratory, Department of Forensic Medicine and Criminology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0003-0001-4624
Rea TaradiDepartment of Pathology and Cytology, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.
Rado ZicDepartment of Surgery, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Ivana IlicDepartment of Pathology and Cytology, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.
Borislav BelevDepartment of Pathophysiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Bosko SkoricSchool of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Dora FabijanovicDepartment of Cardiovascular Diseases, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.
Ivo PlanincDepartment of Cardiovascular Diseases, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.
Maja CikesSchool of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Filip SedlicDepartment of Pathophysiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.

Funding

Croatian Science Foundation IP-2019-04-1449
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiomyopathyheartmitochondriaROSUPRmt

Identifiers

PMID40426970
PMCPMC12108656

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.