Evidence map›Paper›PMID 40426911›Full record

ArticleBiomedicines2025

The IL-6/JAK/STAT3 Axis in Cholangiocarcinoma and Primary Sclerosing Cholangitis: Unlocking Therapeutic Strategies Through Patient-Derived Organoids.

Corinna Boden, Laura K Esser, Leona Dold, Bettina Langhans, Taotao Zhou, Dominik J Kaczmarek, Maria A Gonzalez-Carmona, Tobias J Weismüller, Glen Kristiansen, Jörg C Kalff and 4 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Corinna BodenDepartment of General, Abdominal, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Laura K EsserInstitute of Pathology, University Hospital Bonn, 53127 Bonn, Germany.
Leona DoldDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.
Bettina LanghansDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0001-7733-1092
Taotao ZhouDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.
Dominik J KaczmarekDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0003-0093-7832
Maria A Gonzalez-CarmonaDepartment of Internal Medicine I, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0003-3956-1457
Tobias J WeismüllerVivantes Humboldt-Klinikum, 13509 Berlin, Germany.
Glen KristiansenInstitute of Pathology, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0003-4149-5487
Jörg C KalffDepartment of General, Abdominal, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Michael HölzelInstitute of Experimental Oncology, University Hospital Bonn, 53127 Bonn, Germany.
Hanno MatthaeiDepartment of General, Abdominal, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Marieta I TomaInstitute of Pathology, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-4803-3712
Vittorio BranchiDepartment of General, Abdominal, Thoracic and Vascular Surgery, University Hospital Bonn, 53127 Bonn, Germany.ORCID 0000-0002-6182-835X

Funding

Else Kröner-Fresenius-Stiftung 2014_Kolleg.05
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

baricitinibbiliary tract cancercholangiocarcinomaprimary sclerosing cholangitisSTAT3

Identifiers

PMID40426911
PMCPMC12108797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.