Evidence map›Paper›PMID 40426898›Full record

ArticleBiomedicines2025

"Anti-Bios": Can Local Antibiotics Affect Bone Union in Infected Bone Defects Treated with Degradable Bone Substitutes.

Filippo Vandenbulcke, Salvatore Lorenzo Renne, Giuseppe Anzillotti, Pietro Conte, Giuliano Ravasio, Gabriele Meroni, Federica Riva, Elizaveta Kon

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Filippo VandenbulckeDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0002-4603-659X
Salvatore Lorenzo RenneDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0002-0186-1318
Giuseppe AnzillottiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0001-9327-5350
Pietro ConteDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0001-5425-0652
Giuliano RavasioDepartment of Veterinary Medicine, University of Milan, Via Festa del Perdono 7, 20122 Milan, Italy.
Gabriele MeroniDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Via Pascal 36, 20133 Milano, Italy.ORCID 0000-0003-2772-6410
Federica RivaDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Universita 6, 26900 Lodi, ltaly.ORCID 0000-0002-1270-1627
Elizaveta KonDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0003-0649-2336

Funding

Italian Ministry of Health CO-2018-12367585
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bone healingfracture-related infectionsfracture repairinfected bone defectlocal antibiotics

Identifiers

PMID40426898
PMCPMC12109408

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.