Evidence map›Paper›PMID 40426880›Full record

ReviewBiomedicines2025

Mucosal Immunity: Lessons from the Lower Respiratory and Small Intestinal Epithelia.

Kayle B Dickson, Andrew W Stadnyk, Juan Zhou, Christian Lehmann

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kayle B DicksonDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0009-0001-3016-9240
Andrew W StadnykDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Juan ZhouDepartment of Anesthesiology, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0002-3040-0238
Christian LehmannDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0001-6419-9168

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal epithelia represent a diverse group of tissues that function as a barrier against the external environment and exert a wide variety of tissue-specific secondary functions. This review focuses on the lower respiratory tract and small intestinal epithelia, which serve as two distinct sites within the body with respect to their physiological functions. This review provides an overview of their physiology, including both physiological and mechanical defense systems, and their immune responses, which allow both tissues to tolerate commensal organisms while mounting a response against potential pathogens. By highlighting the commonalities and differences across the two tissue types, opportunities to learn from these tissues emerge, which can inform the development of novel therapeutic strategies that harness the unique properties of mucosal epithelia.

Indexed as

mucosal immunityrespiratory epitheliumsmall intestinal epithelium

Identifiers

PMID40426880
PMCPMC12108762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.