ArticleChildren (Basel, Switzerland)2025
Pandemic as an Organizational Paradigm for Neonatal Care: Long-Term Impact of Mother-Infant Separation Practice During COVID-19.
Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThe hospital organizational model can have an impact on people's health. A critical lesson can be drawn from the pandemic. The possible negative sequelae of the practice of separation of maternal-infant dyads adopted during an infant's first SARS-CoV-2 pandemic infection on infants have not been considered. Our purpose was to investigate the short- and long-term effects on neonates born to SARS-CoV-2 infected mothers of two different mother-infant dyad management strategies after birth (Separation vs. Rooming-In).
methodsThis prospective cohort study enrolled 60 pregnant women who tested positive for SARS-CoV-2 infection and their newborns. We identified two cohorts of study based on mother-infant dyad management after delivery: Cohort A (Separation) and Cohort B (Rooming-In). Inclusion criteria were neonates born from mothers infected with SARS-CoV-2 during the pregnancy undergoing or not undergoing separation. MAIN OUTCOME: Rate of exclusive breastfeeding at 6 months of age was the primary outcome. The rate of mother-infant transmission of SARS-CoV-2 infection, growth, incidence of acute infections and neurodevelopment up to 12 months of life were also evaluated.
resultsIn total, 60 mother-infant dyads (maternal age 30.6 vs. 33.8 years,
conclusionsThe separation practice led to a reduction in the rate of breastfeeding after discharge and to a consequently increased implementation of formula milk, which might justify the alarming increased weight gain of newborns who did not undergo the Rooming-In practice. Given the potential of recurrent outbreaks of other viral pandemics, our results suggest more caution early in life towards the disruption of consolidated procedures that may have long-term consequences. However, the COVID-19 pandemic offered a unique context to observe the effects of temporary mother-infant separation; clinicians should be reassured that the temporary separation practice did not affect neurodevelopment and be aware that it could be considered an option, at least if Rooming-In cannot be carried out due to severe reasons such as lack of staff or adequate space.
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