Evidence map›Paper›PMID 40426725›Full record

ReviewChildren (Basel, Switzerland)2025

Transcatheter Pulmonary Valve Implantation in Congenital Heart Diseases: Current Advances and Future Prospectives.

Mario Giordano, Raffaella Marzullo, Gianpiero Gaio, Maurizio Cappelli Bigazzi, Giovanni Domenico Ciriello, Maria Teresa Palladino, Berardo Sarubbi, Maria Giovanna Russo

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. One Anatomy, Multiple Valve Choices: Interobserver Agreement in Selecting Transcatheter Pulmonary Valve.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Who will be our adult congenital heart disease patient tomorrow?European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mario GiordanoPediatric Cardiology Unit, AORN "Ospedali dei Colli", Monaldi Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0002-0583-5221
Raffaella MarzulloPediatric Cardiology Unit, AORN "Ospedali dei Colli", Monaldi Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Gianpiero GaioPediatric Cardiology Unit, AORN "Ospedali dei Colli", Monaldi Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.ORCID 0000-0002-0016-0966
Maurizio Cappelli BigazziPediatric Cardiology Unit, AORN "Ospedali dei Colli", Monaldi Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Giovanni Domenico CirielloAdult Congenital Heart Disease Unit, AORN "Ospedali dei Colli", Monaldi Hospital, Via Leonardo Bianchi n.1, 80131 Naples, Italy.ORCID 0000-0001-6115-9435
Maria Teresa PalladinoPediatric Cardiology Unit, AORN "Ospedali dei Colli", Monaldi Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Berardo SarubbiAdult Congenital Heart Disease Unit, AORN "Ospedali dei Colli", Monaldi Hospital, Via Leonardo Bianchi n.1, 80131 Naples, Italy.
Maria Giovanna RussoPediatric Cardiology Unit, AORN "Ospedali dei Colli", Monaldi Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary disfunction is frequent in repaired congenital heart diseases. Both pulmonary regurgitation and pulmonary stenosis are possible complications over time. In the past, the surgical approach was the only feasible management but exposed the patient to a redo-surgery with its consequent risks. Nowadays, the development of novel devices and techniques has made possible a transcatheter pulmonary valve implantation. The Melody Transcatheter Pulmonary Valve (TPV) (Medtronic Inc., Minneapolis, MN, USA) and the Edwards Sapien XT and S3 Transcatheter Heart Valve (Edwards Lifesciences LLC, Irvine, CA, USA) are balloon-expandable valvular bioprostheses approved for pulmonary position. Venus P-Valve (Venus Medtech, Shanghai, China) and Harmony TPV (Medtronic Inc., Minneapolis, MN, USA) are self-expandable pulmonary valves. Alterra Adaptive Prestent (Edwards Lifesciences LLC, Irvine, CA, USA) is an hourglass self-expandable stent that reduces the size of large right ventricular outflow tracts, creating a suitable landing zone to implant an Edwards Sapien S3 THV 29 mm. Novel stents and percutaneous valves are being planned and experimented with to widen the field of transcatheter approach. The aim of this review is to describe both the current approaches, strategies, and techniques as well as the future perspective to deal with the patients with significant pulmonary stenosis and/or regurgitation.

Indexed as

grow-up congenital heart diseaseinterventional cardiologypulmonary obstructionpulmonary regurgitationtranscatheter valve replacement

Identifiers

PMID40426725
PMCPMC12109680

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.