Evidence map›Paper›PMID 40426677›Full record

ReviewBrain sciences2025

The Use of Griffiths III in the Appraisal of the Developmental Profile in Autism: A Systematic Search and Review.

Flavia Lecciso, Chiara Martis, Annalisa Levante

Abstract readReview
In one paragraph

Review in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Flavia LeccisoDepartment in Human and Social Sciences, University of Salento, 73100 Lecce, Italy.
Chiara MartisDepartment in Human and Social Sciences, University of Salento, 73100 Lecce, Italy.ORCID 0009-0007-1315-8180
Annalisa LevanteDepartment in Human and Social Sciences, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-3250-3839

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGriffiths III is a child-friendly and play-oriented direct gold-standard measure of a 0-6-year-old child's developmental profile. It is a measure that helps practitioners in detecting the weaknesses in children who have an increased likelihood or a diagnosis of neurodevelopmental disorders, e.g., autism.

objectivesFollowing the PICO protocol, two research questions addressed the current systematic search and review (Prospero registration: CRD42024554286):

methodsSix studies have been reviewed: three case-control studies, a case report study, and two studies examining the effectiveness of early autism-specific interventions. According to the study design, the methodological quality was evaluated using three standardised protocols: STROBE; JBI; CEC.

resultsThe results highlighted that the Language and Communication and Personal-Social-Emotional domains are the most impaired in autistic children and in those with an increased likelihood (RQ1). The results outlined that early target intervention enhanced the same domains (RQ2).

conclusionsIn conclusion, the findings highlight the importance of screening not only for autism traits but also for impairments in language, communication, and socio-emotional skills. The future direction of the results is discussed.

Indexed as

autism interventionautism spectrum disordersCECdevelopmental profileGriffiths IIIJBISTROBE

Identifiers

PMID40426677
PMCPMC12110223

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.