ArticleBrain sciences2025
Theta Burst TMS over the Pre-SMA Improves Inhibitory Control in Gambling Disorder Subjects as Assessed with Stop Signal Task.
Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Neural Markers of Reward Valuation and Impulsive Decision-Making in Mania Risk.JAMA psychiatry · 2026Article
- Attenuated dynamic impulse control in risky action under the escalating risk and reward in gambling disorder.Psychological medicine · 2026Article
- Emerging Interventions in Behavioral Addictions: A Narrative Review of Psychedelics and Neuromodulation.Brain sciences · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundInhibitory control failure represents a central trait in substance and behavioral addictions, which includes patients affected with gambling disorder (GD). In GD patients, research on this trait of the addiction cycle has primarily focused on the use of pharmacological treatments for its assessment. More recently, modification of neural activity using transcranial magnetic stimulation (TMS) has been used to explore the dimensions of GD using patient questionnaires.
methodsHerein, we evaluated the use of continuous Theta burst stimulation (cTBS) over the pre-supplementary motor area (pre-SMA) to determine if it modified inhibitory control in the stop signal task of patients affected by GD when compared with a group of healthy controls without cTBS treatment.
resultsTo the best of our knowledge, our study is the first to report that TMS treatment of GD patients is associated with a behavioral improvement of stop signal reaction time.
conclusionOur results suggest that this TMS-mediated improvement in the efficiency of inhibitory control in GD patients warrants further mechanistic studies in a larger cohort to determine if can be used as a treatment modality.
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