Evidence map›Paper›PMID 40426599›Full record

ArticleBrain sciences2025

Efficacy and Safety of Prolonged Adjuvant Temozolomide Treatment in Glioblastoma: Prospective Study of 81 Patients Undergoing up to 101 Cycles of Treatment.

Giulio Bonomo, Francesco Certo, Erica Grasso, Giuseppa Fiumanò, Davide Barbagallo, Rosario Caltabiano, Giuseppe Broggi, Gaetano Magro, Andrea Maugeri, Antonella Agodi and 6 more

Abstract read
In one paragraph

Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Are conventional and hypofractionated chemoradiotherapy comparable in glioblastoma patients?Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Giulio BonomoDepartment of Neurological Surgery, Policlinico "G. Rodolico-S. Marco" University Hospital, 95121 Catania, Italy.ORCID 0000-0002-4749-7929
Francesco CertoDepartment of Neurological Surgery, Policlinico "G. Rodolico-S. Marco" University Hospital, 95121 Catania, Italy.ORCID 0000-0002-6346-2769
Erica GrassoDepartment of Neurological Surgery, Policlinico "G. Rodolico-S. Marco" University Hospital, 95121 Catania, Italy.
Giuseppa FiumanòInterdisciplinary Research Center on Brain Tumors Diagnosis and Treatment, University of Catania, 95123 Catania, Italy.ORCID 0009-0008-7278-164X
Davide BarbagalloInterdisciplinary Research Center on Brain Tumors Diagnosis and Treatment, University of Catania, 95123 Catania, Italy.ORCID 0000-0001-5331-4554
Rosario CaltabianoDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.ORCID 0000-0001-8591-8010
Giuseppe BroggiDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.ORCID 0000-0003-2576-6523
Gaetano MagroDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.
Andrea MaugeriDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.ORCID 0000-0003-2655-8574
Antonella AgodiDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.ORCID 0000-0002-4405-8162
Fiorenza LatteriInterdisciplinary Research Center on Brain Tumors Diagnosis and Treatment, University of Catania, 95123 Catania, Italy.
Hector SotoparraInterdisciplinary Research Center on Brain Tumors Diagnosis and Treatment, University of Catania, 95123 Catania, Italy.
Giovanni BuscemaDepartment of Anaesthesiology, Policlinico "G. Rodolico-S. Marco" University Hospital, 95123 Catania, Italy.
Corrado SpatolaDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, 95123 Catania, Italy.ORCID 0000-0001-5562-189X
Alessandro PluchinoDepartment of Physics and Astronomy "Ettore Majorana", University of Catania, 95123 Catania, Italy.ORCID 0000-0001-9368-5800
Giuseppe M V BarbagalloDepartment of Neurological Surgery, Policlinico "G. Rodolico-S. Marco" University Hospital, 95121 Catania, Italy.ORCID 0000-0002-7760-6700

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

extendedglioblastomalong-termSTUPPtemozolomide

Identifiers

PMID40426599
PMCPMC12110070

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.