Evidence map›Paper›PMID 40426466›Full record

ReviewBehavioral sciences (Basel, Switzerland)2025

Quality of Life in Caregivers of Patients with Schizophrenia: A Systematic Review of the Impact of Sociodemographic, Clinical, and Psychological Factors.

Corina Gagiu, Vlad Dionisie, Mihnea Costin Manea, Anca Covaliu, Ana Diana Vlad, Ancuta Elena Tupu, Mirela Manea

Abstract readReview
In one paragraph

Review in Behavioral sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Corina GagiuDepartment of Psychiatry and Psychology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Vlad DionisieDepartment of Psychiatry and Psychology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-0075-0050
Mihnea Costin ManeaDepartment of Psychiatry and Psychology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-2492-4529
Anca CovaliuDepartment of Adult Psychiatry, "Prof. Dr. Alexandru Obregia" Clinical Hospital of Psychiatry, 041914 Bucharest, Romania.
Ana Diana VladDepartment of Adult Psychiatry, "Prof. Dr. Alexandru Obregia" Clinical Hospital of Psychiatry, 041914 Bucharest, Romania.
Ancuta Elena TupuDepartment of Scientific Research Methodology, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University of Galati, 800008 Galati, Romania.ORCID 0009-0006-3855-2056
Mirela ManeaDepartment of Psychiatry and Psychology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caregiving for a patient with schizophrenia (PwS) imposes a high burden on caregivers and often affects their quality of life. This systematic review aims to synthesize the current evidence on the sociodemographic and psychological factors of caregivers, as well as patient-related sociodemographic and clinical factors, that may influence caregivers' QoL. The review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive literature search was performed in three major databases-PubMed/Medline, SCOPUS, and Web of Science-to identify original studies examining informal caregivers of PwS and assessing the relationship between caregivers' QoL and various sociodemographic, psychological, or clinical factors. Methodological quality appraisal was performed using the Joanna Briggs Institute checklist. In total, 31 studies were included in the review and discussed at length. Lower QoL was associated with unemployment, older age, female gender, financial difficulties, being unmarried, and lower education. Additionally, increased schizophrenia symptom severity, higher caregiver burden, and elevated levels of depression and anxiety may negatively influence caregivers' QoL. Given these findings, future research should focus on developing tailored interventions to improve caregivers' QoL. Addressing these modifiable risk factors through targeted support programs and policies could significantly enhance caregivers' QoL.

Indexed as

burdencaregiverfamilylife satisfactionquality of lifeschizophreniawell-being

Identifiers

PMID40426466
PMCPMC12109056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.