Evidence map›Paper›PMID 40426226›Full record

ArticleInternational journal of retina and vitreous2025

New surgery technique for refractory macular hole guided by intraoperative OCT: free internal limiting membrane flap and autologous blood clot.

Thais Marino de Azeredo Bastos, Laís Lauria Neves, Letícia Pinheiro de Freitas, David Leonardo Cruvinel Isaac, Antônio Marcelo Barbante Casella, Marcos Pereira Ávila

Abstract read
In one paragraph

Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Thais Marino de Azeredo BastosOphthalmology Reference Center at the Federal University of Goiás (CEROF-UFG), Goiânia, GO, 74605-020, Brazil. thais.mabastos@gmail.com.
Laís Lauria NevesOphthalmology Reference Center at the Federal University of Goiás (CEROF-UFG), Goiânia, GO, 74605-020, Brazil.
Letícia Pinheiro de FreitasOphthalmology Reference Center at the Federal University of Goiás (CEROF-UFG), Goiânia, GO, 74605-020, Brazil.
David Leonardo Cruvinel IsaacOphthalmology Reference Center at the Federal University of Goiás (CEROF-UFG), Goiânia, GO, 74605-020, Brazil.
Antônio Marcelo Barbante CasellaDepartament of Ophthalmology, Estadual de Londrina, UEL, Londrina, PR, Brazil.
Marcos Pereira ÁvilaOphthalmology Reference Center at the Federal University of Goiás (CEROF-UFG), Goiânia, GO, 74605-020, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPresent a new surgical technique which involves using pars plana vitrectomy (PPV) combined with a free internal limiting membrane (ILM) flap anchored by an intraoperatively obtained blood clot, assisted by intraoperative optical coherence tomography (i-OCT).

methodsThis is a prospective interventional non-comparative study with three cases of recurrent or refractory macular hole treated with a new surgical technique using autologous blood clot obtained from the retinal vessels.

resultsThis study included 3 eyes of 3 patients. All patients were previously treated with a PPV and internal limiting membrane peeling. One week post-operatively, all operated eyes showed closure of the macular hole. No complications secondary to the surgical technique occurred.

conclusionThis is a small case series that obtained anatomical success in the macular hole closure with a reproducible technique involving the use of i-OCT to position a free ILM flap, anchored by a blood clot obtained from per operatory retinal bleeding. Further controlled research needs to be done to prove the efficacy.

Indexed as

Blood clotILM peelingi-OCTRefractory macular holeVitrectomy

Identifiers

PMID40426226
PMCPMC12107886

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