Evidence map›Paper›PMID 40426178›Full record

ArticleEye and vision (London, England)2025

The effects of fixation stability, corneal density, and epithelial hyperplasia on the efficacy of astigmatism correction by transepithelial photorefractive keratectomy.

Junjie Yu, Hao Zhou, Minjie Chen, Zhiqiang Yu, Xingtao Zhou, Yishan Qian

Abstract read
In one paragraph

Article in Eye and vision (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Junjie YuDepartment of Ophthalmology, Eye and ENT Hospital, NHC Key Laboratory of Myopia (Fudan University), Fudan University, 83 Fenyang Rd, Shanghai, 200031, People's Republic of China.
Hao ZhouDepartment of Ophthalmology, Eye and ENT Hospital, NHC Key Laboratory of Myopia (Fudan University), Fudan University, 83 Fenyang Rd, Shanghai, 200031, People's Republic of China.
Minjie ChenDepartment of Ophthalmology, Eye and ENT Hospital, NHC Key Laboratory of Myopia (Fudan University), Fudan University, 83 Fenyang Rd, Shanghai, 200031, People's Republic of China.
Zhiqiang YuDepartment of Ophthalmology, Eye and ENT Hospital, NHC Key Laboratory of Myopia (Fudan University), Fudan University, 83 Fenyang Rd, Shanghai, 200031, People's Republic of China.
Xingtao ZhouDepartment of Ophthalmology, Eye and ENT Hospital, NHC Key Laboratory of Myopia (Fudan University), Fudan University, 83 Fenyang Rd, Shanghai, 200031, People's Republic of China.
Yishan QianDepartment of Ophthalmology, Eye and ENT Hospital, NHC Key Laboratory of Myopia (Fudan University), Fudan University, 83 Fenyang Rd, Shanghai, 200031, People's Republic of China. thronebird31@hotmail.com.ORCID http://orcid.org/0000-0001-8698-3316

Funding

Natural Science Foundation of Minhang District, Shanghai China 2023MHZ066Project of Shanghai Health Commission 202340220
6 · The paper itself

Abstract

backgroundTransepithelial photorefractive keratectomy (transPRK) can be safely and predictably performed to correct low-to-high astigmatism. This study explored the effects of fixation stability, corneal density (CD), ocular residual astigmatism (ORA), and the surgically-induced change in the epithelial thickness (ΔET) on the efficacy of astigmatism correction by transPRK.

methodsEighty-three consecutive patients who underwent transPRK to correct myopia and myopic astigmatism were divided into two groups according to refractive astigmatism [high refractive astigmatism (RA) group: ≥ 2.0 D, n = 31; low RA group: < 2.0 D, n = 52]. Fixation stability was evaluated by measuring the lateral movement of the pupil center on the eye tracker images. The CD was measured using a Pentacam Scheimpflug imaging system, epithelial thickness mapping was performed using optical coherence tomography, and the ORA was determined using vector analysis. Multiple linear regression analyses were performed to identify factors associated with the correction index (CI) and angle of error (AOE).

resultsAt 6 months postoperatively, the RA was higher in the high RA group (- 0.66 ± 0.44 D) than in the low RA group (- 0.29 ± 0.29 D, P < 0.001), whereas no significant differences were found in CI or AOE between two groups. Multiple linear regression analyses showed that for the low RA group, preoperative anterior CD of the central 2 mm (CD

conclusionsPostoperative changes in epithelial thickness were associated with the efficacy of transPRK in both the low and high RA groups, whereas the pupil center shift and anterior CD were associated with the efficacy of transPRK in the low RA group.

Indexed as

AstigmatismCorneal densityEpithelial thicknessFixation stabilityTransepithelial photorefractive keratectomy

Identifiers

PMID40426178
PMCPMC12117798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.